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A standard operating procedure (SOP) for platelet-rich plasma (PRP) injection into the ovaries, cervix, and uterus during gynecologic surgery. Covers patient selection and contraindications, PRP prepa...

BACKGROUND: Healthcare professionals' and students' willingness to provide abortion influences access to care and workforce readiness. OBJECTIVE: We conducted a literature synthesis to identify patte...

The duration of endometrial edema has been positively correlated with uterine receptivity and likelihood of pregnancy. Therefore, this study aimed to evaluate whether there is a relationship between t...

OBJECTIVES: Congenital uterine anomalies are the result of abnormal development of the Müllerian ducts and occur in approximately 5% of the general female population. These malformations often remain ...

The primary objective of polycystic ovarian syndrome (PCOS) treatment is to achieve mono-ovulatory cycles, thereby enabling pregnancy and childbirth. Laparoscopic ovarian drilling (LOD) and transvagin...

BACKGROUND: Global fertility rates are declining. In China, the total fertility rate dropped sharply from 5.59 in 1971 to 1.15 in 2021. Chinese university students often lack adequate fertility awaren...

Asthma is a heterogeneous disease characterized by chronic airway inflammation and reversible airflow obstruction. Particularly in severe asthma, airway mucus plugs can contribute to substantial and p...

Objectives. To quantify the impact of state abortion bans on trends in fertility and preterm birth following the June 2022 US Supreme Court decision in Dobbs v Jackson Women's Health Organization. Met...

PURPOSE: To evaluate the clinical relevance of serum progesterone levels on the day of frozen embryo transfer (FET) and the dose of vaginal progesterone gel (Crinone) used for early luteal phase suppo...

A portable, universal, easy-to-preserve alternative of human red blood cells (RBC) has been pursued for decades in order to expand the limited blood supply, with Hemoglobin-Based Oxygen Carrier (HBOC)...

INTRODUCTION: Hyperbaric oxygen therapy (HBOT) is used for various medical conditions. HBOT is demanding and varies in effectiveness. This intensity combined with logistical challenges may lead to pat...

Introducción. Las células madre mesenquimatosas del estroma tienen un gran potencial terapéutico por los efectos antiinflamatorios, antiapoptóticos y proangiogénicos que se pueden obtener a partir de ...

The objective was to test the hypotheses that treatment with a GnRH antagonist, cetrorelix, in combination with progesterone will i) induce synchronous emergence of a new follicular wave and ovulation...

The corpus luteum is a vital yet temporary organ that plays a crucial role in fertility during the luteal phase. An endocrine structure in females exists within the ovary once the ovarian follicle rel...

PROBLEMS: To investigate the impact of anti-endometrial antibodies (EMAb) on pregnancy outcomes in infertile patients undergoing in vitro fertilization (IVF) and to assess the potential value of perso...

BACKGROUND: Simultaneous intrauterine and rudimentary horn pregnancies are exceedingly rare, particularly when one arises from assisted reproduction and the other naturally. Early diagnosis is essenti...

OBJECTIVE: To review the mechanism of action, epidemiology, clinical efficacy, factors influencing treatment outcomes, and limitations of clomiphene citrate (CC). METHODS: A systematic literature sea...

Peipert et al. (1) claim that restorative reproductive medicine (RRM) originated as a political and religious movement with the purpose to limit access to in vitro fertilization (IVF). In so doing, th...

PURPOSE: To summarize assisted reproductive technology (ART) data for 2023 collected through the Japan Society of Obstetrics and Gynecology registry. METHODS AND RESULTS: 625 out of 638 registered AR...

STUDY QUESTION: Is there a difference in live birth rates at 24 months between infertile women with polycystic ovary syndrome (PCOS) who have normal versus abnormal glucose metabolism? SUMMARY ANSWER...

BACKGROUND: Denmark's publicly funded routine HPV vaccination program has included boys born from 2005 onward, leaving earlier birth cohorts of young men potentially unprotected. METHODS: A published...

Male factor infertility acts as a contributing or sole cause in approximately half of all infertility cases, with autoimmunity against spermatozoa-manifested as antisperm antibodies (ASA)-affecting 5-...

A tubo-ovarian abscess (TOA) is a complication of pelvic inflammatory disease (PID) resulting from an ascending infection of the upper genital tract. It is characterized by an inflammatory mass involv...

OBJECTIVE: This debate paper aims to examine the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), whose use in obesity and diabetes management has rapidly expanded, on fertility, cont...

Polycystic ovary syndrome (PCOS), a complex endocrine and metabolic disorder, involves significant dysregulation of the immune system. Natural killer (NK) cells, as key components of innate immunity, ...

INTRODUCTION: Vulvodynia is a chronic vulvar pain condition significantly affecting the quality of life. Its multifactorial etiology is not fully understood, and comprehensive pooled data on associate...

RESEARCH QUESTION: What are the trends and effects of assisted reproductive technology (ART) interventions on the effectiveness and safety of ART carried out in Latin America during 2022. DESIGN: Ret...

Stress is ubiquitous in health and plays a vital role in the pathogenesis of many underlying diseases. Stress and health - this review highlights the interplay between stress and health, focusing on s...

OBJECTIVES: Bone mineral density (BMD) is a critical indicator of osteoporosis (OP). Utilizing the latest multi-omics quantitative trait loci (QTLs) data, we aim to identify novel candidates associate...

STUDY QUESTION: Are maternal concentrations of pregnancy-associated plasma protein-A (PAPP-A) and insulin-like growth factor-1 (IGF-1) influenced by the frozen embryo transfer (FET) protocol in early ...

The objective of this study was to evaluate the effects of exogenous GnRH administration at the beginning of estrus synchronisation in mares during the spring transitional period. Estrus was synchroni...

Serum progesterone (P) levels are critical for endometrial receptivity and implantation in frozen-thawed embryo transfer (FET) cycles. However, the prognostic role of P levels measured on the day of t...

The psychological effects of first-time childbirth on parents have long been a focal point in social science research. This study provides a new perspective by applying demographic transition theory t...

Objective: To assess the effectiveness of an elective to improve students’ knowledge of fertility awareness-based methods for family planning and to determine whether there was a difference in knowled...

Background Severe COVID-19 results in substantial economic burden and impacts quality of life. Assessing how non-hospitalized COVID-19 impacts health utilities during acute infection and long term is ...

# Overview of HFEA public consultation on Choose a Fertility Clinic 2025 Consultation held August-September 2025 on clinic’s main profile statistics on the Choose a Fertility Clinic webpage Published:...

Pelvic inflammatory disease (PID) remains a major cause of tubal factor infertility. Although in vitro fertilization (IVF) has largely replaced reconstructive surgery, selected patients with mild tuba...

Introduction: Assisted reproductive technologies (ART) are widely used to address infertility; however, they are costly, associated with medical risks, and often yield suboptimal clinical outcomes. Na...

Objective: Endometriosis is a chronic gynaecological condition affecting reproductive-aged women. It has been associated with infertility and potential risks for adverse pregnancy outcomes, although p...

# The fertility sector 2024/25 Annual publication on HFEA licensed clinics (1 April 2024 – 31 March 2025) Published: November 2025 [Download the underlying dataset as Excel Worksheet](https://www.hfea...

BACKGROUND: In infertile couples whose male partner has alterations in semen parameters frequently, a comprehensive andrological approach is lacking and approximately 30-50% are classified as idiopath...

Disclosure: A.V. Baaske: None. S. Shirin: None. C. Bos: None. D. Kalidasan: None. J.C. Prior: None. Background: Tanner Breast Stage 3 (TB3, at menarche) and Tanner 5 (TB5, once ovulatory cycles establ...

Disclosure: M. Wood: None. J.C. Prior: None. S. Shirin: None. A. Goshtasebi: None. Breast tenderness and swelling are associated with premenstrual symptoms but have not been well described in healthy,...