Nelson K et al.2025
Open Access
Journal of the Endocrine Society
Disclosure: K. Nelson: None. J. Singer: None. A. Pederson: None. D. Kalidasan: None. J. Prior: None.
Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder that significantly decreases he...
Several studies have evaluated the reliability of using temperature sensors placed in different locations on the body to identify the day of ovulation. However, such demonstrations are lacking for axi...
Wearable Temperature SensorsDevice ValidationTemperature-Based Methods
Background/Objectives: Quantitative urine monitors are increasingly being used for a personalized approach to improve menstrual cycle knowledge and to manage fertility. Although several studies have e...
Iodine, an essential trace element, may play a role in reproductive health through its extrathyroidal actions. This study aimed to investigate the effects of iodine supplementation on oocyte apoptosis...
Declining fertility, overlooked mental health, and reduced life expectancy underscore the urgent need for renewed attention to men's health. A semen analysis, traditionally used to assess fertility, h...
Hormonal contraceptives (HCs) are widely used, yet their effects on emotional and cognitive processes remain poorly understood. This study examined how HC use may influence emotional reactivity, emoti...
Background: Early-life nutritional deprivation may influence lifelong health, but its role in the broader process of reproductive aging remains underexplored. Guided by the Developmental Origins of He...
Background: Self-reported dietary intake varies across menstrual cycle phases, but objective assessments of dietary intake together with appetite and resting metabolic rate (RMR) are limited. This stu...
Energy MetabolismAppetite and Dietary IntakeCrossover Laboratory Studies
**STUDY QUESTION:** What are the data and trends of ART and IUI cycle numbers and their outcomes, and of fertility preservation (FP) interventions, reported in 2020 as compared to previous years?
**S...
Boyle P2025
Open Access
Journal of Restorative Reproductive Medicine
Recently, editorials have been published in reproductive medical journals that have misunderstood and misrepresented the origin and meaning of “restorative reproductive medicine” (RRM).1,2 This term w...
Definition and PrinciplesPatient AutonomyRRM vs IVF
Boyle P et al.2025
Open Access
Journal of Restorative Reproductive Medicine
Objectives: Restorative reproductive medicine (RRM) is an emerging approach that can be used to treat infertility. Our goal was to compare RRM to IVF outcomes in 2019.
Design: We conducted a retrospec...
RRM vs IVF ComparisonLive Birth RatesPrematurity and Birth Weight
Russo LM et al.2025
Open Access
Ecotoxicology and environmental safety
Prior studies have observed impacts of air pollution on semen quality, but timing of exposure during developmental windows of spermatogenesis and impacts of low-to-moderate air pollution is less well ...
Air PollutionMorphology and MotilityEnvironmental Exposures
Fang R et al.2025The Science of the total environment
Understanding and mitigating health risks from poor indoor air quality, particularly fine particulate matter (PM2.5), is critical, yet conventional monitoring methods are costly and require skilled op...
Kotevski DP et al.2025National Perinatal Epidemiology and Statistics Unit, UNSW Sydney
ANZARD annual report on assisted reproductive technology activity, outcomes, and safety across Australia and New Zealand for 2023. Covers fresh-cycle and FET cycle counts, single-embryo transfer rates...
Wainwright E et al.2025
Open Access
Reproductive Health
Background: Fertility rates in the UK are at an all-time low, with infertility affecting approximately 1 in 7 couples. Despite the rising demand for fertility services, fertility awareness, specifical...
Population StudiesMisconceptionsReproductive Education
In many animals, olfactory cues are key for recognizing their sex, kinship, and reproductive status. In humans, it has been proposed that males find female body odors attractive during the ovulatory p...
Park JC et al.2025
Open Access
Cellular & Molecular Immunology
Emerging research underscores the pivotal role of the gut–immune–brain axis, a dynamic bidirectional communication system involving intricate interactions between the gut microbiota, immune responses,...
Prada D et al.2025Environmental health : a global access science source
BACKGROUND: Acetaminophen is the most commonly used over-the-counter pain and fever medication taken during pregnancy, with > 50% of pregnant women using acetaminophen worldwide. Numerous well-designe...
Self-Worth is an over-arching evaluation of a person's sense of individual value. Self-worth, however, is an underappreciated concept. It has rarely been reported related to physiological data; we fou...
Self-Worth and MoodBasal Body TemperatureProspective Ovulation Cohort
Background: Knowledge of the fertile and infertile phases of the menstrual cycle can be applied to conceive or to avoid pregnancy. Fertility intentions and sexual behaviors during the fertile time may...
Creighton Model SystemProspective CohortIntentions and Compliance
Shenoy-Bhangle AS et al.2026Journal of magnetic resonance imaging : JMRI
Endometriosis is a chronic multisystem disease caused by the presence of endometrium-like tissue outside the endometrial canal, inciting inflammation and fibrosis. Transvaginal ultrasound (TVUS) and M...
A one-day meeting was held as a pre-conference to the Catholic Medical Association Annual Educational event in 2024. A panel of eighteen physicians, scientists, and researchers involved in NFP work wa...
Evidence ReviewHormone Monitoring and AppsPostpartum and Perimenopause
Microplastics (MPs) are becoming one of the most serious environmental threats worldwide. They have been shown to induce male reproductive toxicity in animal studies. However, evidence of their advers...
Slaoui A et al.2025
Open Access
International Journal of Surgery Case Reports
This case underscores the effectiveness of a combined laparoscopic and hysteroscopic approach in managing isthmocele, achieving symptom resolution and uterine integrity restoration. Individualized man...
Redondo‐Delgado P et al.2025
Open Access
Acta Obstetricia et Gynecologica Scandinavica
Introduction: Physical activity is known to improve physical and psychological outcomes in pregnant women. While aerobic exercise is typically emphasized in physical activity guidelines for pregnant w...
Exercise and Physical ActivityWeight Gain ManagementExercise Interventions
Currently, there is limited information regarding the presence of chemicals in female underwear and the potential risks involved. This study investigated the levels of ten bisphenols in brassieres and...
Whitley J et al.2025American journal of obstetrics and gynecology
OBJECTIVE: Our objective was to determine if oxytocin discontinuation in the active phase of labor impacts the rate of cesarean delivery compared to continuation of oxytocin.
DATA SOURCES: This study...
Bulletti FM et al.2025
Open Access
Therapeutic advances in reproductive health
Background: Infertility affects around 17.5% of reproductive-aged individuals worldwide, posing significant personal and public health challenges. Although Medically Assisted Reproduction and Assisted...
Integrated Treatment ModelsRestorative vs ARTLaparoscopy and Hysteroscopy
Manniche V et al.2025The International Journal of Risk & Safety in Medicine
Background: Adverse effects of COVID-19 vaccination on human menstrual cycle characteristics have been observed, but limited data are available on the relationship between COVID-19 vaccination status ...
Vaccine and Medication EffectsEnvironmental ExposuresPopulation-Level Analysis
Rovira J et al.2025Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
Global textile production, driven by consumer demand, raises significant concerns about exposure to chemicals in clothing and related products. This review synthesizes evidence (2019-2025) on hazardou...
Damba-Cunningham E et al.2025
Open Access
Journal of Restorative Reproductive Medicine
Background: Fertility awareness-based methods (FABM) of family planning have increased in popularity in recent years. The effectiveness of various methods can vary substantially and can be user depend...
Background Reproductive hormones of the fertile window are often referenced to women in regular cycles, but this may not be representative of the hormonal profiles of women in different circumstances ...
Abstract
Study question
What gut microbiota and metabolic alterations are associated with Polycystic ovary syndrome (PCOS) and linked to adverse pregnancy outcomes (APOs)?
Summary answer
In PCOS, P...
Bernot G et al.2025European Journal of Obstetrics & Gynecology and Reproductive Biology
BACKGROUND: Fertility treatment pathways are complex and lengthy. The current prevalence of infertility makes it a public health issue. The involvement of general practitioners and the training of fer...
Marroquin JM et al.2025
Open Access
Environmental health perspectives
Background: Perand polyfluoroalkyl substances (PFAS) exposure is widespread and has been linked with gynecologic disease. To our knowledge, no study has measured PFAS in endometrial tissue.
Methods: ...
Environmental Chemical ExposureTissue Chemical AnalysisPFAS
# Fertility treatment 2023: trends and figures
Preliminary UK statistics for IVF and DI treatment, storage, and donation
Published: June 2025
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IVF Outcomes and StatisticsFrozen Embryo TransferPopulation-Level Data
Some medical professional organizations have advocated for including the menstrual cycle as a vital sign in adolescence, but not in adulthood. However, documenting menstrual cycle patterns is not rout...
Palmore M et al.2025
Open Access
Environmental epigenetics
Prenatal exposure to air pollution is an important risk factor for child health outcomes, including asthma. Identification of DNA methylation changes associated with air pollutant exposure can provide...
Air Pollution EpigeneticsAsthma and Allergy RiskDNA Methylation
Importance: Identifying atypical body mass index (BMI) trajectories in children and understanding associated, modifiable early-life factors may help prevent childhood obesity.
Objective: To character...
Mortazavi V et al.2025
Open Access
BMC Oral Health
A cell-free particulate enzyme preparation of Mycobacterium smegmatis ATCC 607 catalyzed the transfer of labeled mannose from GDP[14C] mannose to methyl-alpha-D-mannopyranoside (an exogenously added a...
Background: Ovarian hormones affect cardiovascular health yet few sufficient-sized studies with reliable ovulatory documentation have assessed the QTc-hormonal relationship. This study investigated QT...
Breast tenderness and swelling are associated with premenstrual symptoms but are not well described in healthy women. In this 1-year prospective observational study, we examined daily breast tendernes...
The use of hormonal treatments for endometriosis has increased in recent years. Their effectiveness lies in creating a stable hormonal environment, reducing peripheral estrogen levels, and suppressing...
Importance: Medical gaslighting, in which a patient's concerns are dismissed without proper evaluation, has been described anecdotally in vulvovaginal patient care, but has not been quantified.
Objec...
Patient ExperienceGaslighting and DismissalVulvovaginal Conditions
Objectives: This study aimed to elucidate the effects of messenger RNA (mRNA) and inactivated coronavirus disease 2019 (COVID-19) vaccines on ovarian histology and reserve in rats.
Methods: Thirty fe...