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BACKGROUND: For more than three decades, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has provided a framework to quantify health loss due to diseases, injuries, and associate...

Background: Polycystic ovary syndrome (PCOS) is a common, chronic gynaecological condition impacting women of reproductive age. Women with PCOS have hormonal, ovulatory, and metabolic dysfunction resu...

OBJECTIVE: To study the association between previous use of levonorgestrel intrauterine system (LNG-IUS) and endometrial thickness (EMT) in women undergoing in vitro fertilisation (IVF)/intracytoplasm...

The human menopause is hypothesized to be an adaptive trait that allows post-reproductive females to invest in, and avoid reproductive conflict with, their existing offspring and grand-offspring, ther...

Abstract Per- and polyfluoroalkyl substances (PFAS), previously known as perfluorinated compounds (PFC), are a group of synthetic chemicals widely used over the past decades. Their extensive...

BACKGROUND: Endometrial hepatoid adenocarcinoma (HAC) is an exceedingly rare tumor. Histologically, the tumor is predominantly characterized by HAC with additional components, as documented in previou...

DIR Jahrbuch 2024 des Deutschen IVF-Registers. ENGLISH SUMMARY: 2024 Annual Report of the German IVF Registry (Deutsches IVF-Register, DIR). Reports German ART cycle counts, treatment indications, emb...

BACKGROUND: Timely and comprehensive analyses of causes of death stratified by age, sex, and location are essential for shaping effective health policies aimed at reducing global mortality. The Global...

OBJECTIVE: To evaluate the outcomes of embryo donation compared with those of double gamete donation with cryopreserved donor oocytes. DESIGN: Retrospective cohort study. SUBJECTS: The 2016-2019 Soc...

Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals widely used in consumer and industrial products due to their unique physicochemical properties. However, their persistence and bioacc...

BACKGROUND: Endometriosis affects approximately 10% of women of reproductive age and is associated with increased risks of infertility and miscarriage. Although the spontaneous miscarriage rate in wom...

Per- and polyfluoroalkyl substances (PFASs) have been widely used in the production of consumer products globally due to the excellent water and oil resistance and anti-fouling properties. The multipl...

Nationwide survey of JSOG-registered ART facilities on perceptions of disclosing institutional success rates for IVF. Provides context for the JSOG registry's reporting model and clinic-level transpar...

1. Define premature ovarian insufficiency, diagnostic criteria, risk factors and comorbidities. 2. Discuss health concerns, as well as health and hormone management of patients suffering with POI. 3. ...

CARTR Plus 2025 annual report covering Canadian ART activity for treatment cycles completed in 2024. Reports cycles performed, single-embryo transfer rates, clinical pregnancy and live-birth rates, AR...

# National Patient Survey 2024 Survey of UK fertility patients: 2 September - 9 October 2024 Published: March 2025 [Download the underlying dataset as .xlsx](https://www.hfea.gov.uk/media/vf5bxixp/nat...

Sweden national IVF registry report covering 2023 treatments. 26,500 treatments started at 23 clinics (6 public, 17 private). 5,804 live born children (5,508 IVF + 296 IUI-D). Fresh IVF delivery rate ...

BACKGROUND: Reproductive tract disorders are increasingly recognized in aging captive cheetahs (Acinonyx jubatus), a species listed as vulnerable by the International Union for Conservation of Nature....

INTRODUCTION: Among the religious factors that significantly contribute to believers' well-being, research on the personal experience of divine forgiveness (DF) remains in its infancy. The aim of this...

Transition-metal phosphates/phosphides showcase significant promise for energy-related applications because of their high theoretical electrochemical characteristics. However, sluggish electro/ion tra...

PURPOSE: To evaluate the effectiveness and safety of the novel protocol-progestin-primed ovarian stimulation (PPOS) protocol during controlled ovarian hyperstimulation (COH), in patients undergoing in...

Ovarian hyperstimulation syndrome (OHSS) is a serious complication commonly encountered in patients with infertility undergoing ovulation induction therapy. This study investigates histomorphological ...

INTRODUCTION: Attention-Deficit/Hyperactivity Disorder (ADHD) in girls and women is under-recognised and under-researched, despite increasing awareness of clinical challenges and unmet needs. This rev...

INTRODUCTION: Insulin resistance and hyperinsulinaemia significantly influence female hormone regulation and reproductive health. Despite increasing research, the complex pathways by which nutritional...

INTRODUCTION: The design and functionality of injection devices for controlled ovarian stimulation (COS) significantly influence dose accuracy and patient comfort, affecting adherence and treatment su...

BACKGROUND: Intrauterine insemination (IUI) is the first line treatment for conditions such as unexplained or mild male factor infertility. Endometrial thickness (EMT) is an important indicator for pr...

During early pregnancy, human endometrial stromal cells differentiate into secretory decidual cells via a process regulated by ovarian steroid hormones. Decidual cells play a crucial role by secreting...

Large cell neuroendocrine carcinoma (LCNEC) of the endometrium is a rare and aggressive high-grade malignancy, constituting fewer than 1% of endometrial malignancies, with only 33 cases reported in th...

ICMART world report on global assisted reproductive technology activity in 2019. Reports utilization, effectiveness, and safety data submitted from national and regional registries worldwide. Pre-pand...

Abstract The initial setting of telomere length during early life in each individual has a major influence on lifetime risk of aging-associated diseases; however there is limited knowledge of biologic...

Background: Chronic endometritis (CE), frequently asymptomatic, is associated with female infertility. Fallopian tube obstruction (FTO) is also one of the factors contributing to female infertility. M...

STUDY Question: How do endometriosis diagnoses and subtypes reported in administrative health data compare with surgically confirmed disease? SUMMARY ANSWER: For endometriosis diagnosis, we observed ...

STUDY Question: Can semen parameters predict long-term health outcomes in men? SUMMARY ANSWER: There is a lack of evidence to suggest a higher risk of comorbidities in men with poor semen concentrati...

The prevalence of uterine isthmocele, also known as a uterine niche, has risen in parallel with increasing cesarean section (CS) rates, affecting approximately 60% of women depending on their history ...

Background: Maternal hormonal contraception use has been associated with childhood leukemia risk. However, studies are few and often based on self-reported information. Methods: Using registry data f...

Study question: How should premature/primary ovarian insufficiency (POI) be diagnosed and managed based on the best available evidence from published literature?Summary answerThe current guideline pro...

STUDY Question: How should premature/primary ovarian insufficiency (POI) be diagnosed and managed, based on the best available evidence from published literature? SUMMARY ANSWER: The current guidelin...

Background: The combined hormonal contraceptive (CHC) with ethinylestradiol and progestins is the most widely used contraceptive method among young women and is used by millions worldwide. However, un...

Background: Premature ovarian insufficiency/failure (POI/POF) is a significant issue for women of reproductive age. Anti-Müllerian hormone (AMH) is a potential biomarker of ovarian reserve, but its cl...

RTAC Code of Practice (Issue 9) governing accreditation requirements for reproductive technology units operating in Australia and New Zealand. Sets standards for clinical, laboratory, and quality-mana...

Objectives: To evaluate the experiences of perimenopausal and postmenopausal women in British Columbia, their perceptions of expected reproductive aging, and potential concerns about endometrial cance...

# Family formations in fertility treatment 2022 Preliminary UK family type statistics for IVF and DI treatment, storage, and donation Published: November 2024 [Download the underlying dataset as .xlsx...

STUDY Objective: To compare outcomes of vaginal surgery in women with moderate or severe symptomatic cesarean scar defect (with or without residual myometrium). Design: Retrospective cohort study. Set...

No standard criteria exist for how to perform a diagnostic laparoscopy. This case series provides evidence of the importance of standardized, reproducible techniques. A single non-oncologic gynecologi...

Processed foods, accounting for most consumable food categories today, contain considerable amounts of food additives. Food additives are substances added to food products to improve taste, consistenc...