Department of Gynecology and Obstetrics, Bicetre Hospital, Le Kremlin Bicetre, France (all authors); Faculty of Medicine, University Paris Saclay, Le Kremlin Bicetre, France (Drs. Fernandez and Cap...ROR
To compare outcomes of vaginal surgery in women with moderate or severe symptomatic cesarean scar defect (with or without residual myometrium).
Design
Retrospective cohort study.
Setting
Gynecology department of a teaching hospital.
Patients
Fifty-three women, between January 2014 and December 2019, underwent vaginal surgery for symptomatic cesarean scar defect: 20 women with moderate defect (with residual myometrium) and 33 with severe defect (without residual myometrium).
Interventions
Vaginal surgical approach to repair cesarean scar defect. MEASUREMENTS AND
Main Results
surgery by comparing the myometrial residual thickness before and after surgery. The secondary objectives were evaluation of vaginal surgery efficacy on symptoms resolution, per and postoperative courses, and subsequent fertility. Failure rate was evaluated as the need for a second surgery. After vaginal surgery, the residual myometrium significantly increased from 2.4 mm ± 0.9 mm to 6.6 mm ± 2.4 mm (p <.01) in the moderate group and from 0 mm to 4.4 mm ± 2.2 mm (p <.01) in the severe group. The prevalence of abnormal uterine bleeding was significantly reduced after surgery in both groups (p <.01). Pelvic pain was significantly reduced only in the moderate group (p <.01). The rate of complications (5% vs 9.1%) and second surgery (15% vs 24.2%) were not significantly different between moderate and severe groups, respectively. The median time to conceive (7 months vs 12 months); pregnancy rates (84.6% vs 68.2%); and live birth rates (76.9% vs 50%) were not statistically significant in the moderate and severe groups respectively, with 90% of pregnancies occurring naturally. Women delivered by cesarean section at 38 weeks of gestation in both groups, and no uterine rupture was reported.
Conclusion
Despite the absence of residual myometrium, vaginal repair of severe cesarean scar defect was effective in increasing myometrial thickness, in relieving bleeding symptoms, and in allowing to achieve pregnancy.
PMID 39577558 39577558 DOI 10.1016/j.jmig.2024.10.023 10.1016/j.jmig.2024.10.023
Cite this article
Bardet, L., Berl, Q., Debras, E., Pourcelot, A. G., Fernandez, H., & Capmas, P. (2025). Is Vaginal Repair a Good Option for Severe Cesarean Scar Defect? Comparison of Women With or Without Residual Myometrium. *Journal of minimally invasive gynecology*, *32*(4), 352-357. https://doi.org/10.1016/j.jmig.2024.10.023
Bardet L, Berl Q, Debras E, Pourcelot AG, Fernandez H, Capmas P. Is Vaginal Repair a Good Option for Severe Cesarean Scar Defect? Comparison of Women With or Without Residual Myometrium. J Minim Invasive Gynecol. 2025;32(4):352-357. doi:10.1016/j.jmig.2024.10.023
Bardet, L., et al. "Is Vaginal Repair a Good Option for Severe Cesarean Scar Defect? Comparison of Women With or Without Residual Myometrium." *Journal of minimally invasive gynecology*, vol. 32, no. 4, 2025, pp. 352-357.
Tulandi T et al., 2016Journal of Minimally Invasive Gynecology
The objective of this study was to evaluate the prevalence of cesarean scar defects and its clinical manifestations in reproductive-aged women. We performed a systematic review following the Preferred...
Surgery > Uterine Surgery > Cesarean Scar Defect RepairGeneral OB/GYN > Cesarean Complications > Scar Defect ManifestationsInfertility > Uterine Factors > Cesarean Scar Defect and Fertility
Kremer TG et al., 2019
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An isthmocele, a cesarean scar defect or uterine niche, is any indentation representing myometrial discontinuity or a triangular anechoic defect in the anterior uterine wall, with the base communicati...
Iannone P et al., 2019
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Revista Brasileira De Ginecologia E Obstetricia : Revista Da Federacao Brasileira Das Sociedades De Ginecologia E Obstetricia
Objective: The aim of the present study was to perform a comprehensive review of the literature to provide a complete and clear picture of isthmocele-a hypoechoic area within the myometrium at the sit...
Surgery > Uterine Surgery > Cesarean Scar Defect RepairGeneral OB/GYN > Uterine Pathology > Isthmocele Diagnosis and ManagementPregnancy > Cesarean Section > Long-Term Scar Complications
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