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Public Awareness, Perceptions, and Preferences in Fertility Treatment: Secondary Analysis of Two Public Surveys
This secondary analysis examined two independent U.S. surveys (J.L. Partners, N=1002; McLaughlin & Associates, N=1000) investigating public perspectives on fertility treatments. Initial support for IV...
The Association Between History of Infertility and Dietary Practices: A Cross-Sectional Study Among Preconception Females
Objective: To evaluate the extent to which a history of infertility is associated with adherence to specific diets among reproductive-aged females. Design: Cross-sectional analysis. Subjects: Between ...
Gestational progesterone restores menstrual cycle in PCOS patients via enhancing ovary estrogen production
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age, typically characterized by irregular menstrual cycles. Our study found that postpartum menstrual...
Endometriosis phenotypes and staging in relation to lipid biomarkers: Findings from the ENDO Cohort Study
Background: Endometriosis has been linked to cardiometabolic alterations, but whether these associations vary by disease severity or phenotype is unclear. We examined lipid profiles across endometrios...
Neonatal characteristics of children conceived with in vitro fertilization or intrauterine insemination compared with sibling births from unassisted conceptions
Objective: To examine birth outcomes between children conceived with in vitro fertilization (IVF) or intrauterine insemination (IUI) and sibling births from unassisted conceptions. Design: Retrospect...
Endometriosis Surgery: Debates About Restorative Reproductive Medicine
For many patients with endometriosis, laparoscopic surgery is the most effective treatment to alleviate severe chronic pelvic pain and improve quality of life. Because endometriosis is common among in...
The influence of the menstrual cycle on muscle injuries - a systematic review and meta-analysis
This systematic review and meta-analysis examined the relationship between menstrual cycle phases and the incidence of muscle injuries in female team sport athletes, following PRISMA 2020 and PERSiST ...
The False Promise of Restorative Reproductive Medicine-Restricting Access to Care in the Name of "Natural" Medicine
Infertility affects 1 in 6 people globally (and up to a third of physicians) and is recognized by the World Health Organization and the American Medical Association as a disease. Since 1978, the devel...
Incident endometriosis diagnosis and anti-müllerian hormone (AMH): how surgical staging and typology relate to serum AMH levels
Background: Endometriosis is a chronic, gynecologic condition in which tissue similar to the lining of the uterus implants throughout the body. Women with endometriosis have a higher prevalence of inf...
Influence of Tubal Patency on Endometriosis Recurrence: A Retrospective Matched Case-control Study
STUDY OBJECTIVE: To study whether bilateral nonpatency of fallopian tubes is correlated with a lower recurrence rate of endometriosis. DESIGN: Retrospective 2:1 matched case-control study. SETTING: Un...
Disordered eating behaviors during adolescence and risk of endometriosis: a prospective cohort study
Objective: Disordered eating behaviors may impact the gynecologic health of adolescents through effects on menstrual cycle function and body size; however, few studies have evaluated these association...
Association between the Modified Cardiometabolic Index and Endometriosis in an American Cohort: Insights from a Cross-sectional Analysis
"Reply of the authors: ""Response to ""The illusion of reproductive choice: how restorative reproductive medicine violates informed consent for infertility treatment"""""
Multidimensional factors increase menstrual distress in patients with endometriosis
Human Endometriotic Lesion-Derived Small Extracellular Vesicles Impair Macrophage Function in the Peritoneal Microenvironment
"Uterine closure after cesarean delivery: surgical technique, biological rationale, and clinical implications."
Normal uterine function depends on cyclical regeneration and the capacity to sustain pregnancy. A cesarean incision represents an injury to this remarkable organ. Although the uterus possesses excepti...
Global, regional, and national burden of breast cancer among females, 1990-2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023
The Role of Nutrition on the Pathogenesis of Endometriosis
Lipid metabolism drives dietary effects on T cell ferroptosis and immunity
Reply of the authors: "Response to "The illusion of reproductive choice: how restorative reproductive medicine violates reproductive autonomy and informed consent"" by Frank-Herrmann et al
Response to "The illusion of reproductive choice: how restorative reproductive medicine violates reproductive autonomy and informed consent"
Peipert et al. (1) claim that restorative reproductive medicine (RRM) originated as a political and religious movement with the purpose to limit access to in vitro fertilization (IVF). In so doing, th...
"Response to ""The illusion of reproductive choice: how restorative reproductive medicine violates informed consent for infertility treatment"""
The effects of glucagon-like peptide-1 receptor agonists on fertility, contraception, and pregnancy: clinical perspectives
OBJECTIVE: This debate paper aims to examine the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs), whose use in obesity and diabetes management has rapidly expanded, on fertility, cont...
A meta-umbrella review of risk factors for vulvodynia: evidence from demographic, psychosocial, and biomedical domains
INTRODUCTION: Vulvodynia is a chronic vulvar pain condition significantly affecting the quality of life. Its multifactorial etiology is not fully understood, and comprehensive pooled data on associate...
Total and live birth prevalence of singleton pregnancies with Down's syndrome in Scotland between 2000 and 2021: a population-based study
BACKGROUND: Down's syndrome (DS) is the most common chromosomal congenital condition diagnosed in pregnancy. Antenatal screening for DS is available in Scotland, and in September 2020, non-invasive pr...
Hemoglobin-based oxygen carrier: What we have learned and where we are heading?
A portable, universal, easy-to-preserve alternative of human red blood cells (RBC) has been pursued for decades in order to expand the limited blood supply, with Hemoglobin-Based Oxygen Carrier (HBOC)...
From bench to bedside: unlocking the anti-inflammatory, antioxidant, and anticancer promise of curcumin in gynecology
Curcumin, a bioactive polyphenol derived from turmeric (Curcuma longa), has garnered substantial attention for its potent anti-inflammatory, antioxidant, and antineoplastic properties. This review exp...
Progesterone levels on the day of the β-hCG test predict pregnancy outcomes in FET cycles
Serum progesterone (P) levels are critical for endometrial receptivity and implantation in frozen-thawed embryo transfer (FET) cycles. However, the prognostic role of P levels measured on the day of t...
Ursolic acid, a pentacyclic triterpene from Ochrosia elliptica Labill leaves and its role in the management of polycystic ovary syndrome (PCOS)
Ursolic Acid (UA), a naturally occurring pentacyclic triterpene, was isolated from Ochrosia elliptica. Polycystic Ovary Syndrome (PCOS) a prevalent endocrine disorder characterized by hyperandrogenism...
The Doula's Role in Reducing Postpartum Depression: A Narrative Review
BACKGROUND: Postpartum depression (PPD) affects 10% to 20% of mothers, with higher rates among marginalized communities. Mental health issues contribute to 22.7% of pregnancy-related deaths. Doulas pr...
Autonomy under pressure: a scoping review of social egg freezing in the bottom quintile of the gender gap index
BACKGROUND: Social Egg Freezing (SEF), often promoted in Western contexts as a means to enhance reproductive autonomy, has seen varied uptake in countries with wider gender disparities. In such settin...
Synergistic roles of follicle-stimulating hormone and testosterone in Sertoli cell proliferation and testicular function in roosters
Spermatogenesis relies on the intricate interactions between testicular somatic cells and germ cells. While follicle-stimulating hormone (FSH) and testosterone (T) are considered pivotal regulatory fa...
Changes in Frequency and Health of Live Births Following State Abortion Bans
Objectives. To quantify the impact of state abortion bans on trends in fertility and preterm birth following the June 2022 US Supreme Court decision in Dobbs v Jackson Women's Health Organization. Met...
Decision regret and shared decision-making in patients undergoing hyperbaric oxygen therapy
INTRODUCTION: Hyperbaric oxygen therapy (HBOT) is used for various medical conditions. HBOT is demanding and varies in effectiveness. This intensity combined with logistical challenges may lead to pat...
Impact of an expanded male catch-up HPV vaccination program on the clinical and economic burden of HPV-associated diseases in Denmark: a modeling study
BACKGROUND: Denmark's publicly funded routine HPV vaccination program has included boys born from 2005 onward, leaving earlier birth cohorts of young men potentially unprotected. METHODS: A published...
Integrative prenatal imaging and genomic testing in fetal congenital heart defects: Insights from a 30-year retrospective study
OBJECTIVE: To assess the combined role of prenatal imaging and stepwise genetic testing in diagnosing fetal congenital heart defects (CHDs) over a 30-year period, focusing on CHD subtypes, extracardia...
Healthcare professionals' and students' willingness to perform abortion: A systematic review and meta-analysis, 2014-2025
BACKGROUND: Healthcare professionals' and students' willingness to provide abortion influences access to care and workforce readiness. OBJECTIVE: We conducted a literature synthesis to identify patte...
Comparative analysis of stress markers, metabolic health, and gut microbiota in healthy and disabled dogs in long-term shelters in Thailand
Regular welfare assessments are essential for identifying and addressing the physical, behavioral, and emotional needs of shelter dogs, thereby ensuring their well-being and improving chances for adop...
Impact of glucose metabolism abnormalities on live birth rate in South-East Asian women with polycystic ovary syndrome
STUDY QUESTION: Is there a difference in live birth rates at 24 months between infertile women with polycystic ovary syndrome (PCOS) who have normal versus abnormal glucose metabolism? SUMMARY ANSWER...
Application of 3D printing in the evaluation of a clinically significant congenital uterine anomaly
OBJECTIVES: Congenital uterine anomalies are the result of abnormal development of the Müllerian ducts and occur in approximately 5% of the general female population. These malformations often remain ...
Serum progesterone and vaginal gel dose in artificial-cycle frozen embryo transfer: association with pregnancy outcome
PURPOSE: To evaluate the clinical relevance of serum progesterone levels on the day of frozen embryo transfer (FET) and the dose of vaginal progesterone gel (Crinone) used for early luteal phase suppo...
Early pregnancy concentrations of pregnancy-associated plasma protein-A (PAPP-A) and insulin-like growth factor-1 (IGF-1) following frozen embryo transfer: secondary analyses from a randomized controlled trial
STUDY QUESTION: Are maternal concentrations of pregnancy-associated plasma protein-A (PAPP-A) and insulin-like growth factor-1 (IGF-1) influenced by the frozen embryo transfer (FET) protocol in early ...
Synergistic cross-linking and mineralization for wet-tough, biocompatible collagen-based hernia patches
Natural polymer-based hernia patches exhibit biocompatibility and biodegradability compared with non-degradable polypropylene (PP) meshes; however, their clinical translation has been severely hampere...
Platelet-Rich Plasma in Sperm Processing for Assisted Reproductive Technology: Molecular Mechanisms, Clinical Applications, and Future Directions
Male infertility contributes to nearly half of infertile couples, with asthenozoospermia and oligoasthenoteratozoospermia as predominant factors. Despite advancements in sperm processing techniques, t...
Omnipresence of Stress: The Hidden Crisis
Stress is ubiquitous in health and plays a vital role in the pathogenesis of many underlying diseases. Stress and health - this review highlights the interplay between stress and health, focusing on s...
Screening Using the Edinburgh Postnatal Depression Scale at Delivery Discharge as a Predictor of Postpartum Depression
BACKGROUND: The objective of this study was to determine if Edinburgh Postnatal Depression Scale (EPDS) scores at delivery discharge are predictive of EPDS scores at 2-6 weeks postpartum. METHOD: Thi...
Clomiphene citrate in the management of anovulation: a review of mechanisms, outcomes, and clinical challenges
OBJECTIVE: To review the mechanism of action, epidemiology, clinical efficacy, factors influencing treatment outcomes, and limitations of clomiphene citrate (CC). METHODS: A systematic literature sea...
Global burden of adverse effects of medical treatment from 1990 to 2021: a Global Burden of Disease Study 2021
BACKGROUND/AIMS: This study aims to evaluate the global burden of adverse effects of medical treatment (AEMT) using data from the Global Burden of Disease Study (GBD) 2021. METHODS: Data were extract...