Gonadotropins
Gonadotropins are protein hormones that regulate gonadal function. In the clinical fertility context, the term commonly refers to injectable preparations used for ovulation induction or ovarian stimulation: recombinant FSH (follitropin alfa/beta) and human menopausal gonadotropin (hMG, containing FSH and LH activity). These agents directly stimulate ovarian follicle growth, bypassing the hypothalamic-pituitary axis entirely.
In NaProTECHNOLOGY practice, injectable gonadotropins are generally considered after oral ovulation induction agents (letrozole or clomiphene) have been evaluated, or for specific indications such as hypogonadotropic anovulation where hypothalamic drive is absent. When used, gonadotropin cycles are closely monitored by serial transvaginal ultrasound to detect multi-follicular development and reduce the risk of ovarian hyperstimulation syndrome (OHSS). The guiding philosophy is mild stimulation: doses are kept as low as effective. In Restorative Reproductive Medicine, ovulation induction with gonadotropins remains a targeted intervention directed at a diagnosed underlying cause rather than a default escalation pathway.
This content is for educational purposes only and does not constitute medical advice. Consult an RRM clinician or healthcare provider for guidance specific to your situation.