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Body weight and body composition of depot medroxyprogesterone acetate users

Dal'Ava N et al., 2014 Contraception

Objectives: Weight gain is a concern with the contraceptive depot-medroxyprogesterone acetate (DMPA); however, this issue remains controversial. The objective of this study was to compare body weight ...

Contraception/Comparison > Hormonal Contraception > DMPA Side EffectsContraception/Comparison > Non-Hormonal vs Hormonal > Weight and Body CompositionGeneral OB/GYN > Metabolic Health > Contraceptive-Related Weight Changes

Use of ovulation predictor kits as adjuncts when using fertility awareness methods (FAMs): a pilot study

Leiva R et al., 2014 Journal of the American Board of Family Medicine : JABFM

Purpose: Difficult clinical signs such as confusing cervical mucus or erratic basal body temperature can make the use of fertility awareness methods (FAMs) difficult in some cases. The goal of this st...

Fertility Awareness > Methods > Ovulation Predictor KitsFertility Awareness > Efficacy > Adjunct Tools for Cycle MonitoringResearch Methodology > Pilot Studies > Crossover Design

Cohort efficacy study of natural family planning among perimenopause age women

Fehring RJ et al., 2014 Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN

Objective: To determine the efficacy of using natural family planning (NFP) methods to avoid unintended pregnancy among women of perimenopause age (i.e., age 40-55 years). Design: A secondary analysis...

Fertility Awareness > Efficacy > Perimenopause UsePerimenopause/Menopause > Fertility Management > Natural Family PlanningResearch Methodology > Prospective Cohort > Survival Analysis

Inherited Thrombophilia

Phillippe HM et al., 2014 Journal of Pharmacy Practice

Thrombophilia alters normal hemostasis, shifting the balance in favor of thrombus formation. Inherited conditions include factor V Leiden (FVL), prothrombin G20210A mutation, deficiencies in natural a...

Reproductive Endocrinology > Thrombophilia > Inherited Coagulation DisordersPregnancy > Complications > Thrombophilia and Thrombosis RiskGeneral OB/GYN > Hematologic Disorders > Factor V Leiden and Prothrombin Mutation

Interstitial cystitis associated with primary Sjögren's syndrome successfully treated with a combination of tacrolimus and corticosteroid: A case report and literature review

Ueda Y et al., 2016 Modern rheumatology

We report a case of interstitial cystitis (IC) associated with primary Sjögren's syndrome (SS) successfully controlled with combination therapy of tacrolimus and a corticosteroid. In 2011, a 69-year-o...

General OB/GYN > Urologic Conditions > Interstitial CystitisDiagnostics > Autoimmune Disorders > Sjögren Syndrome Urinary Complications

Oral contraceptives and breast cancer risk overall and by molecular subtype among young women

Beaber EF et al., 2014 Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology

Background: Evidence suggests that recent oral contraceptive (OC) use is associated with a small increased breast cancer risk; yet risks associated with contemporary OC preparations and by molecular s...

Contraception/ComparisonGeneral OB/GYN

Recommendations for the laboratory-based detection of Chlamydia trachomatis and Neisseria gonorrhoeae--2014

No Authors Listed, 2014 MMWR. Recommendations and Reports : Morbidity and Mortality Weekly Report. Recommendations and Reports

This report updates CDC's 2002 recommendations regarding screening tests to detect Chlamydia trachomatis and Neisseria gonorrhoeae infections (CDC. Screening tests to detect Chlamydia trachomatis and ...

Infertility > Infectious Causes > STI ScreeningDiagnostics > Laboratory Testing > Nucleic Acid Amplification TestsGeneral OB/GYN > Sexually Transmitted Infections > Detection Guidelines

Choice of lumbar spine bone density reference database for fracture prediction in men and women: a population-based analysis

William D Leslie et al., 2014 Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry

The diagnosis of osteoporosis in men is controversial, although most studies demonstrate similar fracture rates for men and women with the same level of hip bone mineral density (BMD). Whether this ap...

Bone HealthPerimenopause/Menopause

Hormonal contraceptive use and breast cancer in Thai women

Poosari A et al., 2014 Open Access Journal of Epidemiology

Background: Breast cancer is the most common cancer in women worldwide. We investigated the association of hormonal contraceptive use and breast cancer in Thai women. Methods: A cohort study was cond...

Contraception/ComparisonGeneral OB/GYN

Serum leptin levels and reproductive function during the menstrual cycle

Ahrens K et al., 2014 American journal of obstetrics and gynecology

Objective: The purpose of this study was to investigate the role of leptin on reproductive hormones and ovulation. Study Design: The BioCycle Study (2005-2007) followed 259 healthy premenopausal wome...

Menstrual CycleReproductive Endocrinology

Cardiovascular and general safety of a 24-day regimen of drospirenone-containing combined oral contraceptives: final results from the International Active Surveillance Study of Women Taking Oral Contraceptives

Dinger J et al., 2014 Contraception

Objectives: The "International Active Surveillance Study of Women Taking Oral Contraceptives" investigated the risks of shortand long-term use of an extended 24-day regimen of drospirenone and ethinyl...

Contraception/Comparison > Oral Contraceptives > Cardiovascular SafetyContraception/Comparison > Side Effects > Venous ThromboembolismResearch Methodology > Prospective Cohort Studies > Pharmacovigilance

The association between endometriosis and chronic endometritis

Takebayashi A et al., 2014 Open Access PloS One

Objective: To evaluate the association between endometriosis and chronic endometritis. Methods: Endometrial specimens were obtained from 71 patients, 34 with endometriosis (endometriosis group) and 3...

EndometriosisInfertilityDiagnostics

Differential glucocorticoid receptor-mediated effects on immunomodulatory gene expression by progestin contraceptives: implications for HIV-1 pathogenesis

Hapgood JP et al., 2014 Am J Reprod Immunol

Whether hormonal contraceptives increase HIV-1 acquisition, transmission and disease progression are critical questions. Clinical research has been hampered by a lack of understanding that different p...

Contraception/Comparison > Injectable Contraceptives > HIV RiskContraception/Comparison > Progestin Types > Glucocorticoid Receptor ActivityReproductive Endocrinology > Progestins > Immunomodulatory Effects

Variability in the morphologic assessment of human sperm: use of the strict criteria recommended by the World Health Organization in 2010

Wang Y et al., 2014 Fertility and Sterility

OBJECTIVE: To determine the variability in the recognition of normal sperm and various sperm defects using the strict criteria recommended by the World Health Organization (5th edition, 2010). DESIGN...

Andrology > Semen Analysis > Morphology AssessmentDiagnostics > Sperm Evaluation > WHO Criteria VariabilityResearch Methodology > Observer Agreement > Reproductive Diagnostics

The effect of physical activity across the menstrual cycle on reproductive function

Ahrens KA et al., 2014 Annals of epidemiology

Purpose: To evaluate the association between physical activity (PA) across the menstrual cycle and reproductive function. Methods: The BioCycle Study (2005-2007) followed 259 healthy premenopausal wo...

Menstrual Cycle > Hormonal Patterns > Physical Activity EffectsReproductive Endocrinology > Ovulatory Function > Exercise InfluenceMenstrual Cycle > Anovulation > Lifestyle Factors

Combination contraceptives: effects on weight

Gallo MF et al., 2014 The Cochrane Database of Systematic Reviews

Background: Weight gain is often considered a side effect of combination hormonal contraceptives, and many women and clinicians believe that an association exists. Concern about weight gain can limit ...

Contraception/ComparisonResearch Methodology

Oral contraceptives, hormone replacement therapy and breast cancer risk: a cohort study of 16 928 women 48 years and older

Thorbjarnardottir T et al., 2014 Open Access Acta Oncologica (Stockholm, Sweden)

Background: Findings on potential interactive effects of oral contraceptives (OCs) and hormone replacement therapy (HRT) on breast cancer risk have been inconsistent. We aimed to use population-based ...

Contraception/Comparison > Oral Contraceptives > Breast Cancer RiskPerimenopause/Menopause > Hormone Replacement Therapy > Breast CancerContraception/Comparison > Long-term Effects > Cancer Risk

In vitro effects of coital lubricants and synthetic and natural oils on sperm motility

Sandhu RS et al., 2014 Fertility and Sterility

OBJECTIVE: To evaluate the effects of coital lubricants and oils on sperm motility. DESIGN: Comparative prospective in vitro study. SETTING: University Andrology laboratory. PATIENT(S): Twenty-two ...

Pregnancy > Conception Optimization > Lubricant Effects on SpermAndrology > Sperm Function > Motility AssessmentInfertility > Lifestyle Factors > Lubricant Selection

Timing of oral contraceptive use and the risk of breast cancer in BRCA1 mutation carriers

Kotsopoulos J et al., 2014 Breast Cancer Research and Treatment

It is not clear if early oral contraceptive use increases the risk of breast cancer among young women with a breast cancer susceptibility gene 1 (BRCA1) mutation. Given the benefit of oral contracepti...

Contraception/Comparison > Oral Contraceptives > Breast Cancer RiskContraception/Comparison > Genetic Risk Factors > BRCA1 Mutation CarriersGeneral OB/GYN > Cancer Risk > Hereditary Breast Cancer

The Genetics of Infertility: Current Status of the Field

Zorrilla M et al., 2014 Current Genetic Medicine Reports

Infertility is a relatively common health condition, affecting nearly 7% of all couples. Clinically, it is a highly heterogeneous pathology with a complex etiology that includes environmental and gene...

InfertilityReproductive EndocrinologyAndrology

15. The menstrual cycle and lipid levels

Mumford S et al., 2014 Handbook of diet and nutrition in the menstrual cycle, periconception and fertility
Menstrual Cycle > Hormonal Patterns > Lipid MetabolismReproductive Endocrinology > Metabolic Effects > Lipid VariationMenstrual Cycle > Biomarkers > Cardiovascular Risk Markers

Incarcerated Omentum With Tamponade Effect in the Uterine Perforation Scar After Dilation and Curettage: A Case Report

Kim KW, 2014 Open Access Journal of medical cases

Perforation of the uterus is the most common immediate complication at the time of dilatation and curettage (D&C). We experienced the case of a patient with intra-abdominal extrusion of fetal part and...

General OB/GYN > Surgical Complications > Uterine PerforationGeneral OB/GYN > Procedures > Dilation and CurettageSurgery > Laparoscopic Repair > Uterine Injury

A meta-analysis of the association of fracture risk and body mass index in women

Helena Johansson et al., 2014 J Bone Miner Res

Several recent studies suggest that obesity may be a risk factor for fracture. The aim of this study was to investigate the association between body mass index (BMI) and future fracture risk at differ...

Bone Health > Fracture Risk > Body Mass Index AssociationPerimenopause/Menopause > Osteoporosis > Fracture Risk FactorsResearch Methodology > Meta-Analysis > Fracture Epidemiology

HFEA Fertility Trends and Figures 2012

Human Fertilisation and Embryology Authority, 2014
Contraception/Comparison > Assisted Reproduction > National StatisticsInfertility > Assisted Reproductive Technology > Population Trends

Reproductive factors and breast cancer: a case-control study in tertiary care hospital of North India

Bhadoria AS et al., 2013 Indian Journal of Cancer

Background: Clinical, animal, and epidemiological studies have clearly demonstrated that cancer is a hormonally mediated disease and several factors that influence hormonal status or are markers of ch...

General OB/GYN > Breast Cancer > Reproductive Risk FactorsContraception/Comparison > Oral Contraceptives > Breast Cancer RiskResearch Methodology > Case-Control Studies > Cancer Epidemiology

The effect of oral contraceptive pills and the natural menstrual cYCLe on arterial stiffness and hemodynamICs (CYCLIC)

Yu A et al., 2013 Journal of Hypertension

Background: Over 100 million women currently use oral contraceptive pills (OCPs) worldwide. However, little is known about the effects of OCPs on arterial stiffness and hemodynamics. Furthermore, whet...

Reproductive Endocrinology > Hormonal Effects > Cardiovascular HemodynamicsContraception/Comparison > Oral Contraceptives > Cardiovascular EffectsMenstrual Cycle > Cycle Phases > Hemodynamic Variations

Efficacy of achieving pregnancy with fertility-focused intercourse

Mu Q et al., 2013 MCN. The American Journal of Maternal Child Nursing

Purpose: To compare pregnancy rates when women have intercourse on self-estimated high and peak fertile days and when they only have intercourse on low fertile days during the fertile window (FW). STU...

Fertility Awareness > Methods > Electronic Hormonal MonitoringInfertility > Natural Conception > Fertility-Focused IntercourseFertility Awareness > Efficacy > Pregnancy Achievement Rates

Trace elements and endometriosis: the ENDO study

Pollack AZ et al., 2013 Reproductive toxicology (Elmsford, N.Y.)

There has been limited study of trace elements and endometriosis. Using a matched cohort design, 473 women aged 18-44 years were recruited into an operative cohort, along with 131 similarly aged women...

EndometriosisDiagnostics

The immune modifying effects of amino acids on gut-associated lymphoid tissue

Ruth MR et al., 2013 Open Access Journal of Animal Science and Biotechnology

The intestine and the gut-associated lymphoid tissue (GALT) are essential components of whole body immune defense, protecting the body from foreign antigens and pathogens, while allowing tolerance to ...

General OB/GYN > Nutrition > Amino Acids and Immune FunctionResearch Methodology > Review Articles > Nutritional Immunology

Negative spinal bone mineral density changes and subclinical ovulatory disturbances--prospective data in healthy premenopausal women with regular menstrual cycles

Danni Li et al., 2013 Epidemiologic Reviews

Subclinical ovulatory disturbances (anovulation or short luteal phases within normal-length menstrual cycles) indicate lower progesterone-to-estrogen levels. Given that progesterone plays a bone forma...

Menstrual Cycle > Ovulatory Disturbances > Subclinical AnovulationBone Health > Bone Mineral Density > Premenopausal Bone LossReproductive Endocrinology > Progesterone > Bone Formation Role

The definition, aetiology, presentation, diagnosis and management of previous caesarean scar defects

Allornuvor GF et al., 2013 Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology

Caesarean sections are the most commonly performed surgical procedures involving the uterus in fertile women. Typically, this surgery involves a transverse incision in the anterior lower uterine segme...

Surgery > Uterine Surgery > Caesarean Scar DefectGeneral OB/GYN > Caesarean Section > ComplicationsDiagnostics > Imaging > Uterine Scar Assessment