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The significance of C-reactive protein in the diagnosis of chorioamnionitis in cases of premature rupture of the membranes

Chaaban M et al., 1988

Journal de gynecologie, obstetrique et biologie de la reproduction, 17(8), 1045-1049

PMID 3235786 Source

Abstract

We have retrospectively studied the changes in the level of C-reactive protein (CRP) and of white blood cells in 82 patients who had premature rupture of the membranes between the 20th and the 36th week of pregnancy in order to estimate the possibility of prenatal screening for amnion infections in early rupture of the membranes. The level of CRP was shown to be quickly and significantly raised in cases of clinical or histological chorioamnionitis, whereas the change in maternal leucocytes alters little and later. The level of CRP can be worked out as an early biological marker which is sensitive and cheap in the clinical supervision of cases with early rupture of the membranes.

Topics

Pregnancy > Preterm Birth > Risk FactorsPregnancy > Complications > Infection
c-reactive protein chorioamnionitis, premature rupture membranes infection screening, crp marker preterm prelabor rupture, early amnion infection detection, maternal inflammatory markers pprom, prenatal screening chorioamnionitis biomarkers, premature membrane rupture second trimester, biological markers early prom management, white blood cells vs crp pregnancy infection

Cite this article

Chaaban, M., Jauniaux, E., Nasreddine, S., Jabry, S., Duchateau, J., & Wilkin, P. (1988). [The significance of C-reactive protein in the diagnosis of chorioamnionitis in cases of premature rupture of the membranes]. *Journal de gynecologie, obstetrique et biologie de la reproduction*, *17*(8), 1045-1049.

Keywords

C-Reactive Protein, Chorioamnionitis, Female, Fetal Membranes, Premature Rupture, Gestational Age, Humans, Infant, Newborn, Pregnancy, Retrospective Studies, Sepsis

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