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Maternal Iron and Vitamin D Status during the Second Trimester Is Associated with Third Trimester Depression Symptoms among Pregnant Participants in the APrON Cohort

Evanchuk JL et al. 2023 Open Access The Journal of Nutrition

Background: The maternal status of multiple micronutrients during pregnancy and postpartum and their potential associations with maternal health outcomes are largely undescribed. Objectives: This stu...

Iron and Vitamin D StatusAntenatal DepressionMicronutrient Assessment in Pregnancy

Vaginal micronised progesterone for the prevention of hypertensive disorders of pregnancy: A systematic review and meta-analysis

Melo P et al. 2023 Open Access BJOG : an International Journal of Obstetrics and Gynaecology

Background: Treatment with vaginal progesterone reduces the risk of miscarriage and preterm birth in selected high-risk women. The hypothesis that vaginal progesterone can reduce the risk of hypertens...

Hypertensive DisordersProgesterone SupplementationSystematic Review and Meta-Analysis

State of the Fertility Sector 2022/2023

Human Fertilisation and Embryology Authority 2023

# State of the fertility sector 2022/23 Annual publication on HFEA licensed centres (1st April 2022 – 31st March 2023) Published: 12th September 2023 [Download the underlying dataset as .xlsx](https:/...

Regulatory OversightIVF Clinic RegulationFertility Treatment Regulation

Repair of Isthmocele Following Embolization of Uterine Arteriovenous Malformation

Huang D et al. 2023 Journal of Minimally Invasive Gynecology

Objective: To present a case of concurrent uterine arteriovenous malformation (AVM) and isthmocele, treated with ethylene vinyl alcohol copolymer (EVAC) embolization of the AVM followed by robotic ist...

Robotic Isthmocele RepairUterine AVM EmbolizationCesarean Scar Defect Repair

Evidence-based guideline: unexplained infertility

Romualdi D et al. 2023 Hum Reprod

Guideline Group on Unexplained Infertility; Romualdi D(1), Ata B(2)(3), Bhattacharya S(4), Bosch E(5), Costello M(6)(7), Gersak K(8), Homburg R(9), Mincheva M(10), Norman RJ(7)(11), Piltonen T(12), ...

Placental histology for targeted risk assessment of recurrent spontaneous preterm birth

Suresh S et al. 2023 American Journal of Obstetrics and Gynecology

Background: Spontaneous preterm birth significantly increases the risk for a recurrent preterm birth. Only a few identifiable clinical risk factors can be referenced in counseling for recurrent preter...

Recurrent Preterm BirthPlacental PathologyProgesterone Supplementation for Preterm Birth

Impact of thyroid autoantibodies and serum TSH level on clinical IVF outcomes

Moon KY et al. 2023 Open Access Taiwanese Journal of Obstetrics & Gynecology

Objective: This study aimed to investigate the impact of thyroid autoantibodies and serum TSH levels on clinical IVF outcomes. Materials and Methods: This study included 260 Korean women scheduled fo...

Thyroid Autoimmunity and IVFIVF Outcomes and Thyroid FunctionTSH Thresholds in Fertility

Lack of evidence that progesterone in ovulatory cycles causes breast cancer

Gompel A et al. 2023 Climacteric : the Journal of the International Menopause Society

A recent Perspective article asserted that progesterone secretion during ovulatory cycles is the cause of breast cancer. However, we challenge most of the evidence developed in this publication. First...

Breast Cancer RiskCancer Risk AssessmentProgesterone Safety Evidence

Examining the co-occurrence of endometriosis and polycystic ovarian syndrome

Schliep KC et al. 2023 Open Access AJOG Global Reports

Background: Polycystic ovarian syndrome and endometriosis are 2 of the most common reproductive disorders among women but are thought to be unrelated. Objective: This study aimed to examine the overl...

PCOS Co-OccurrenceEndometriosis OverlapEndometriosis vs PCOS

3-Tier Endometriosis Symptom Self-Assessment Tool

Whittaker N. 3-Tier Endometriosis Symptom Self-Assessment Tool. RRM Academy. 2023

An evidence-based, 3-tier endometriosis self-assessment developed by Dr. Naomi Whittaker, board-certified OB/GYN (MIGS, NFPMC, FCI). Evaluates 36 symptoms across three tiers of clinical suspicion -- V...

Self-AssessmentClinical Tools

Completion of Fetal Anatomy Evaluations in Women With Body Mass Index ≥ 50 kg/m(2)

Buskmiller C et al. 2023 Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine

Objectives: As maternal body mass index (BMI) increases, fetal anatomy ultrasound becomes more challenging, less sensitive, and less likely to be complete. We sought to report our experience of incomp...

Fetal Anatomy UltrasoundUltrasound ChallengesUltrasound Completion Rates

Risk of Stroke Hospitalization After Infertility Treatment

Sachdev D et al. 2023 JAMA network open

IMPORTANCE: Stroke accounts for 7% of pregnancy-related deaths in the US. As the use of infertility treatment is increasing, many studies have sought to characterize the association of infertility tre...

Don't ignore perimenopause

Prior JC et al. 2023 Open Access CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

We agree with Lega and colleagues[1][1] that menopausal hormone therapy (MHT) has been shown in randomized controlled trials (RCTs) to be effective and safe for treating problematic vasomotor symptoms...

Perimenopause/MenopauseReproductive Endocrinology

The Utilization of Low Dose Naltrexone for Chronic Pain

Poliwoda S et al. 2023 CNS Drugs

Naltrexone is a mu-opioid receptor antagonist with a long half-life compared with naloxone. Both of these drugs, along with others, were developed with the intention of reversing the effects of opioid...

Women's health, hormonal balance, and personal autonomy

Segarra I et al. 2023 Open Access Frontiers in Medicine

Hormone-based contraception disrupts hormonal balance, creating artificial states of anovulation and threatening women's health. We reviewed its main adverse effects and mechanisms on accelerated ovar...

Contraception/ComparisonReproductive Endocrinology

Endometriosis, Oocyte, and Embryo Quality

Latif S et al. 2023 Open Access Journal of Clinical Medicine

Endometriosis is a common finding among women with infertility, and women who are diagnosed with endometriosis are almost twice as likely to experience infertility. Mechanisms by which endometriosis c...

EndometriosisInfertility

Cardiovascular Safety of Testosterone-Replacement Therapy

Lincoff AM et al. 2023 The New England journal of medicine

BACKGROUND: The cardiovascular safety of testosterone-replacement therapy in middle-aged and older men with hypogonadism has not been determined. METHODS: In a multicenter, randomized, double-blind, ...

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