Increased rate of preterm deliveries in untreated women with luteal phase deficiencies. Preliminary report

Author affiliations (2)
  • University Hospital and Clinics ROR
  • Cooper University Hospital ROR

Gynecologic and Obstetric Investigation, 33(3), 183-184, 1992

DOI 10.1159/000294877 PMID 1612531

Abstract

Some randomized studies have suggested a significant beneficial effect of 17-hydroxyprogesterone caproate in the prevention of preterm labor [1, 2], The therapy in both studies was initiated at approximately 12-16 weeks and continued until labor.

We considered the possibility that a deficient proges­ terone effect during the first trimester may lead to a higher rate of preterm deliveries. A retrospective study was thus performed comparing the incidence of preterm versus full-term pregnancies in women with luteal phase defects who were either treated or not treated with proges­ terone supplementation during the first trimester.

Topics

luteal phase deficiency preterm delivery risk, progesterone supplementation first trimester preterm prevention, luteal phase defect progesterone preterm labor, Check JH luteal phase defect preterm delivery, 17-hydroxyprogesterone caproate preterm labor prevention, first trimester progesterone deficiency preterm birth, progesterone treatment luteal phase defect pregnancy outcomes, untreated luteal phase deficiency preterm delivery rate, retrospective study progesterone supplementation preterm birth, luteal insufficiency pregnancy complications prematurity
PMID 1612531 1612531 DOI 10.1159/000294877 10.1159/000294877

Cite this article

Check, J. H., Lee, G., Epstein, R., & Vetter, B. (1992). Increased rate of preterm deliveries in untreated women with luteal phase deficiencies. Preliminary report. *Gynecologic and obstetric investigation*, *33*(3), 183-184. https://doi.org/10.1159/000294877

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