Follicular growth and corpus luteum function in women with unexplained infertility, monitored by ultrasonography and measurement of daily salivary progesterone
L A Joyce, F. P. Median, M M Finn, P F Fottrell, J P Gosling, F P Meehan, D F Tallon
Ovarian function was evaluated over a minimum of 3 consecutive menstrual cycles from each of 41 women with unexplained infertility. Follicular development and ovulation were monitored using real time ultrasonography and luteal function was evaluated by daily salivary progesterone measurement. In 129 spontaneous cycles, normal single ovulations were detected in 121 (93.8%). Luteal phase insufficiency was identified in 21 (17.4%) of these 121 cycles and this was a recurrent phenomenon in the cycles of 5 of the 41 women (12.2%). A successful pregnancy was seen only in association with consistently normal salivary progesterone profiles or where the empirical use of clomiphene citrate therapy had corrected previously diagnosed luteal phase insufficiency. Basal body temperature records or mid-luteal serum progesterone measurements were less satisfactory indices of luteal function than a salivary progesterone profile.
unexplained infertility follicular growth ultrasound monitoring, salivary progesterone corpus luteum function infertility, luteal phase insufficiency unexplained infertility recurrent, daily salivary progesterone profile luteal function evaluation, clomiphene citrate luteal phase deficiency correction pregnancy, Finn Gosling salivary progesterone unexplained infertility, basal body temperature versus salivary progesterone luteal assessment, consecutive menstrual cycle monitoring ultrasonography infertility, mid-luteal serum progesterone vs salivary progesterone comparison, ovulation detection real time ultrasound luteal insufficiency
PMID 2626978 2626978 DOI 10.3109/09513598909152469 10.3109/09513598909152469
Cite this article
Finn, M. M., Gosling, J. P., Tallon, D. F., Joyce, L. A., Meehan, F. P., & Fottrell, P. F. (1989). Follicular growth and corpus luteum function in women with unexplained infertility, monitored by ultrasonography and measurement of daily salivary progesterone. *Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology*, *3*(4), 297-308. https://doi.org/10.3109/09513598909152469
Finn MM, Gosling JP, Tallon DF, Joyce LA, Meehan FP, Fottrell PF. Follicular growth and corpus luteum function in women with unexplained infertility, monitored by ultrasonography and measurement of daily salivary progesterone. Gynecol Endocrinol. 1989;3(4):297-308. doi:10.3109/09513598909152469
Finn, M. M., et al. "Follicular growth and corpus luteum function in women with unexplained infertility, monitored by ultrasonography and measurement of daily salivary progesterone." *Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology*, vol. 3, no. 4, 1989, pp. 297-308.
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