0

C-reactive protein: a limited test for managing patients with preterm labor or preterm rupture of membranes?

Ernest JM et al., 1987

American journal of obstetrics and gynecology, 156(2), 449-454

DOI 10.1016/0002-9378(87)90306-1 PMID 3826184 Source

Abstract

C-reactive protein has been used to identify patients at high risk for infectious morbidity with preterm labor or preterm rupture of membranes. In this article we report on 104 patients with preterm labor symptoms (n = 45) or preterm rupture of the membranes (n = 59) and serial evaluations of C-reactive protein measured by latex agglutination and laser nephelometry. The simple, inexpensive latex method appears comparable to the laser method in predicting infectious morbidity and can be used clinically. Elevated C-reactive protein values before delivery predict infectious morbidity in only 8% to 29% of patients, and up to 18% of patients with serious infections may be misdiagnosed as having normal C-reactive protein values before delivery.

Topics

Pregnancy > Outcomes > ComplicationsPregnancy > Preterm Birth > Risk Factors
c-reactive protein preterm labor infection, crp test preterm rupture membranes, inflammatory marker pprom chorioamnionitis, c-reactive protein predictive value preterm birth, latex agglutination crp preterm labor, infection screening preterm membrane rupture, crp infectious morbidity pregnancy, biomarker preterm delivery infection risk

Cite this article

Ernest, J. M., Swain, M., Block, S. M., Nelson, L. H., Hatjis, C. G., & Meis, P. J. (1987). C-reactive protein: a limited test for managing patients with preterm labor or preterm rupture of membranes?. *American journal of obstetrics and gynecology*, *156*(2), 449-454. https://doi.org/10.1016/0002-9378(87)90306-1

Keywords

C-Reactive Protein, Chorioamnionitis, Female, Fetal Diseases, Fetal Membranes, Premature Rupture, Humans, Infections, Obstetric Labor, Premature, Pregnancy

Related articles