Trends in copper versus hormonal intrauterine device breakage reporting within the United States' Food and Drug Administration Adverse Event Reporting System
Contraception, 118, 109909, 2023
Abstract
Objective
To examine trends in national reporting of broken intrauterine devices (IUDs).
Study design
We enumerated IUD device "breakage" reports in the Food and Drug Administration Adverse Event Reporting System from inception (1998) until February 2022. We explored associations of breakage with IUD type (copper versus hormonal), year reported, reporter (consumer versus clinician), and patient characteristics (age and weight).
Results
We identified 4144 breakage reports for copper versus 2140 for hormonal IUDs. Among the 170,215 adverse events reported, breaks were disproportionately reported for copper (9.6%) versus hormonal (1.7%) IUDs.
Conclusion
National pharmacovigilance data suggests disproportionate breakage in copper versus hormonal IUDs though the true prevalence of breaks cannot be calculated from this dataset.
Topics
Cite this article
Latack, K., & Nguyen, B. (2022). Trends in copper versus hormonal intrauterine device breakage reporting within the United States' Food and Drug Administration Adverse Event Reporting System. *Contraception*, *118*, 109909. https://doi.org/10.1016/j.contraception.2022.10.011
Latack K, Nguyen B. Trends in copper versus hormonal intrauterine device breakage reporting within the United States' Food and Drug Administration Adverse Event Reporting System. Contraception. 2022;118:109909. doi:10.1016/j.contraception.2022.10.011
Latack, Kyle, and Brian Nguyen. "Trends in copper versus hormonal intrauterine device breakage reporting within the United States' Food and Drug Administration Adverse Event Reporting System." *Contraception*, vol. 118, 2022, pp. 109909.
Keywords
United States, Female, Humans, Intrauterine Devices, Medicated, Copper, United States Food and Drug Administration, IUD-removal, LARC, Pharmacovigilance