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The significance of luteal phase deficiency on fertility: a diagnostic and therapeutic approach

J Balasch, Manuel Márquez, I Burzaco, M Creus, J A Vanrell

  • Hospital Clínic de Barcelona ROR

Human Reproduction (Oxford, England), 1(3), 145-147

DOI 10.1093/oxfordjournals.humrep.a136370 PMID 3114310

Abstract

Luteal phase deficiency, diagnosed by endometrial biopsy, was found in 1 out of 25 control fertile women and in 46 out of 355 infertile patients, a difference that was not significant. It was also found in 19 [corrected] out of 60 patients with early recurrent abortion which was significantly higher than in controls and in infertile patients. Pregnancy outcome was evaluated in treated and untreated groups of patients diagnosed as having luteal phase deficiency. Our data suggest that treatment improved the results of pregnancy in patients with recurrent abortion, but not in infertile patients.

Topics

Infertility > Luteal Phase Deficiency > Diagnosis and TreatmentReproductive Endocrinology > Luteal Phase Defect > Endometrial BiopsyPregnancy > Recurrent Pregnancy Loss > Luteal Phase Support
luteal phase deficiency endometrial biopsy diagnosis infertility, luteal phase defect treatment recurrent abortion outcomes, progesterone supplementation luteal phase deficiency pregnancy, endometrial biopsy dating luteal insufficiency fertile vs infertile, Balasch luteal phase deficiency recurrent miscarriage, luteal phase defect prevalence infertile patients versus controls, treated versus untreated luteal phase deficiency pregnancy outcome, recurrent early abortion luteal insufficiency diagnosis, luteal phase deficiency clinical significance fertility treatment, endometrial maturation delay infertility recurrent pregnancy loss
PMID 3114310 3114310 DOI 10.1093/oxfordjournals.humrep.a136370 10.1093/oxfordjournals.humrep.a136370

Cite this article

Balasch, J., Creus, M., Márquez, M., Burzaco, I., & Vanrell, J. A. (1986). The significance of luteal phase deficiency on fertility: a diagnostic and therapeutic approach. *Human reproduction (Oxford, England)*, *1*(3), 145-147. https://doi.org/10.1093/oxfordjournals.humrep.a136370

Keywords

Abortion, Habitual/diagnosis/drug Therapy/etiology, Adult, Biopsy, Chorionic Gonadotropin/therapeutic Use, Clomiphene/analogs & Derivatives/therapeutic Use, Endometrium/drug Effects/pathology, Female, Humans, Infertility, Female/diagnosis/drug Therapy/etiology, Luteal Phase, Menstruation Disturbances/complications/diagnosis, Pregnancy, Progesterone/analogs & Derivatives/therapeutic Use, Chorionic Gonadotropin, Clomiphene, Progesterone

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