0

The effect of fertility drugs and in vitro methods on the outcome of 106 triplet pregnancies

Lipitz S et al., 1993

Fertility and sterility, 60(6), 1031-1034

DOI 10.1016/s0015-0282(16)56405-x PMID 8243681 Source

Abstract

Objective

To compare the effect of fertility drugs and IVF on the outcome of triplet pregnancies.

Design

Prospective clinical study.

Setting

A single university medical center.

Patients

One hundred six consecutive triplet pregnancies treated from 1984 through 1992.

Main outcome measures

The frequency of pregnancy loss, livebirths, and antenatal and neonatal complications was compared in spontaneous, clomiphene citrate (CC), menotropins, and IVF triplet pregnancies.

Results

Eighty-one of the 106 (76.4%) triplet pregnancies progressed beyond 25 weeks, comprising 6 of 7 (85.7%) spontaneous pregnancies, 13 of 16 (81.2%) CC induced, 44 of 56 (78.6%) menotropin induced, and 18 of 27 (66.6%) IVF gestations. There were no significant differences in the stillbirth and neonatal mortality rates according to the mode of conception. The mean gestational ages and the mean birth weights were similar in the four groups. The frequency of premature contractions, premature rupture of membranes, cesarean section, and neonatal complications were similar in the ovulation induction and IVF pregnancies.

Conclusion

Triplet pregnancies after ovulation induction and IVF have a similar outcome.

Topics

Infertility > Female Factor > Ovulatory DysfunctionPregnancy > Outcomes > ComplicationsGeneral OB/GYN > Epidemiology > Prevalence
triplet pregnancy outcomes after fertility treatment, clomiphene citrate triplet pregnancy, menotropins triplet pregnancy complications, ivf triplet pregnancy outcomes, ovulation induction multiple pregnancy, triplet pregnancy stillbirth rates, triplet pregnancy gestational age, fertility drug triplet outcomes comparison, triplet pregnancy neonatal mortality, multiple gestation after ovulation induction, triplet pregnancy prematurity, clomiphene versus menotropins triplet outcomes

Cite this article

Lipitz, S., Seidman, D. S., Alcalay, M., Achiron, R., Mashiach, S., & Reichman, B. (1993). The effect of fertility drugs and in vitro methods on the outcome of 106 triplet pregnancies. *Fertility and sterility*, *60*(6), 1031-1034. https://doi.org/10.1016/s0015-0282(16)56405-x

Keywords

Adult, Birth Weight, Clomiphene, Embryo Transfer, Female, Fertilization in Vitro, Fetal Death, Gestational Age, Humans, Menotropins, Ovulation Induction, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Prospective Studies, Triplets

Related articles