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The effect of alpha-tocopherol on premenstrual symptomatology: a double-blind study

London RS et al., 1983

Journal of the American College of Nutrition, 2(2), 115-122

DOI 10.1080/07315724.1983.10719916 PMID 6350402 Source

Abstract

In a double-blind, randomized dose-response study, 75 women with benign breast disease were administered a written questionnaire in which they scored the severity of premenstrual syndrome (PMS) symptoms before and after two months of treatment with placebo or alpha-tocopherol (150, 300, or 600 IU/day). Controlling for age and pretreatment scores, alpha-tocopherol had a significantly greater effect than placebo, improving three of the four classes of PMS symptoms. These findings suggest that vitamin E supplementation may be of value in women with severe PMS symptoms.

Topics

Menstrual Cycle > Disorders > PMDDMenstrual Cycle > Physiology > Luteal PhaseGeneral OB/GYN > Clinical Practice > Guidelines
vitamin e premenstrual syndrome, alpha-tocopherol pms treatment, nutritional supplements menstrual symptoms, premenstrual syndrome natural treatment, benign breast disease pms, vitamin supplementation menstrual cycle, non-hormonal pms management, tocopherol premenstrual symptomatology, dietary interventions menstrual disorders, pms double blind trial, menstrual cycle nutritional support, premenstrual tension vitamin therapy

Cite this article

London, R. S., Sundaram, G. S., Murphy, L., & Goldstein, P. J. (1983). The effect of alpha-tocopherol on premenstrual symptomatology: a double-blind study. *Journal of the American College of Nutrition*, *2*(2), 115-122. https://doi.org/10.1080/07315724.1983.10719916

Keywords

Adolescent, Adult, Clinical Trials As Topic, Dose-Response Relationship, Drug, Double-Blind Method, Female, Humans, Menstruation Disturbances, Middle Aged, Premenstrual Syndrome, Syndrome, Vitamin E

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