Simulation of the normal menstrual cycle in Kallman's syndrome by pulsatile administration of luteinizing hormone-releasing hormone (LHRH)

The Journal of clinical endocrinology and metabolism, 51(1), 173-175

DOI 10.1210/jcem-51-1-173 PMID 6247361 Source

Abstract

The administration of small doses of LHRH at 2-hourly intervals over a 27 day period to a 24-year old patient with Kallman's syndrome resulted in ovulation as indicated by: (1) a biphasic temperature response, (2) anatomical changes in the ovaries demonstrated by ultrasound, and (3) the pattern of circulating gonadotropin and gonadal steroid concentrations.

Topics

pulsatile gnrh ovulation induction, lhrh treatment kallmann syndrome, gonadotropin releasing hormone infertility, pulsatile hormone therapy anovulation, physiologic ovulation induction protocol, gnrh pump therapy fertility, kallmann syndrome fertility treatment, hypothalamic amenorrhea lhrh therapy, cervical mucus monitoring ovulation induction, basal body temperature biphasic response

Cite this article

Crowley, W. F., & McArthur, J. W. (1980). Simulation of the normal menstrual cycle in Kallman's syndrome by pulsatile administration of luteinizing hormone-releasing hormone (LHRH). *The Journal of clinical endocrinology and metabolism*, *51*(1), 173-175. https://doi.org/10.1210/jcem-51-1-173

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