The aim of this study was to investigate the association between risk factors and breast cancer in Turkish women. In a hospital-based case-control study in Istanbul, 405 patients with histologically confirmed breast cancer were compared with 1050 controls, who were admitted to different departments of the same hospital. Unadjusted odds ratios (ORs) and 95% confidence intervals (CIs) for each risk factor were obtained from logistic regression analyses. Risk factors for breast cancer were found to be early menarche age (OR 3.87, 95% CI 2.46-6.08), use of alcohol (OR 3.87, 95% CI 1.79-8.37), history of diabetes (OR 3.31, 95% CI 2.36-4.64) or hypertension (OR 3.44, 95% CI 2.07-5.71), oral contraceptive use (OR 1.98, 95% CI 1.38-2.85) and hormone replacement therapy (HRT) use (OR 1.94, 95% CI 1.15-3.29). The findings of the present study indicated that history of diabetes or hypertension, use of alcohol, oral contraceptive and HRT, never having breastfed and delayed age at first birth associated with changing of lifestyle led to an increased risk of breast cancer in Turkish women.
oral contraceptive use breast cancer risk case-control, hormone replacement therapy breast cancer Turkish women, early menarche breast cancer risk factor, breastfeeding protective effect breast cancer Turkish population, delayed age first birth breast cancer risk, Beji Reis breast cancer risk factors Turkey hospital-based, diabetes hypertension breast cancer association women, oral contraceptive HRT breast cancer logistic regression, lifestyle changes breast cancer risk developing countries, reproductive risk factors breast cancer case-control study
PMID 17371428 17371428 DOI 10.1111/j.1365-2354.2006.00711.x 10.1111/j.1365-2354.2006.00711.x
Cite this article
Beji, N. K., & Reis, N. (2007). Risk factors for breast cancer in Turkish women: a hospital-based case-control study. European journal of cancer care, 16(2), 178-184. https://doi.org/10.1111/j.1365-2354.2006.00711.x
Beji NK, Reis N. Risk factors for breast cancer in Turkish women: a hospital-based case-control study. Eur J Cancer Care (Engl). 2007;16(2):178-184. doi:10.1111/j.1365-2354.2006.00711.x
Beji, Nezihe Kızılkaya, and Nesrin Reis. "Risk factors for breast cancer in Turkish women: a hospital-based case-control study." European journal of cancer care, vol. 16, no. 2, 2007, pp. 178-184.
Keywords
Contraceptives, Oral
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