Platelet-rich plasma therapy and reproductive medicine

  • Universidade Federal do Rio Grande do Sul ROR

Journal of Assisted Reproduction and Genetics, 35(5), 753-756

DOI 10.1007/s10815-018-1159-8 PMID 29564738

Abstract

Reports on clinical uses of platelet-rich plasma (PRP) have dramatically increased in the last decade. Indications for PRP therapy range from muscle and skeletal injuries to hair re-growth. More recently evidences have shown its positive effects in promoting endometrial and follicular growth and gestation in assisted reproduction cycles. We discuss the putative role of PRP on endometrial receptivity, with a brief history of its applications in research and clinical therapies. Despite its widespread uses in medicine, the mechanisms through which PRP exerts its regenerative effects are only postulated, not based on scientific data. There is an unmet need for advanced research to corroborate present findings in the clinical scenario.

Topics

Bos-Mikich de Oliveira Frantz platelet-rich plasma therapy reproductive medicine review, PRP ovarian rejuvenation endometrial receptivity Asherman syndrome fertility applications, autologous platelet-rich plasma growth factors tissue regeneration reproductive organs, PRP thin endometrium poor responder premature ovarian insufficiency treatment, Journal Assisted Reproduction Genetics 2018 PRP reproductive medicine review, platelet concentrate PDGF TGF-beta FGF VEGF endometrial ovarian regeneration, PRP intrauterine infusion endometrial growth implantation rate improvement, PRP intraovarian injection follicle development ovarian reserve restoration, platelet-rich plasma fertility treatment emerging evidence systematic appraisal, regenerative medicine PRP reproductive tissue healing clinical case series
PMID 29564738 29564738 DOI 10.1007/s10815-018-1159-8 10.1007/s10815-018-1159-8

Cite this article

Bos-Mikich, A., De Oliveira, R., & Frantz, N. (2018). Platelet-rich plasma therapy and reproductive medicine. *Journal of assisted reproduction and genetics*, *35*(5), 753-756. https://doi.org/10.1007/s10815-018-1159-8

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