Plasma gonadotropin and sex steroid hormone levels during early, midfollicular, and midluteal phases of women with luteal phase defects

Cook CL, Rao CV, Yussman MA

doi:10.1016/s0015-0282(16)47175-x

Plasma gonadotropin and sex steroid hormone levels during early, midfollicular, and midluteal phases of women with luteal phase defects

C V Rao, Christine Cook, M A Yussman

University of Louisville ROR

Fertility and Sterility, 40(1), 45-48

DOI 10.1016/s0015-0282(16)47175-x PMID 6407879

Abstract

Thirteen women with luteal phase defects (LPD) confirmed by endometrial biopsies and 14 with histologically normal endometria were studied for early follicular and midfollicular phase follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels and for midluteal phase progesterone, estrogen, testosterone, and prolactin levels. The results showed that the women with LPD had significantly lower FSH levels and FSH/LH ratios in the early and midfollicular phases. LH levels, however, were similar in the LPD and normal women. During the midluteal phase, the LPD women showed significantly lower levels of progesterone and estrogen and normal levels of testosterone and prolactin. These findings reaffirm the prevailing concept that events surrounding follicular growth and development can indeed influence the quality of that cycle's corpus luteum. Furthermore, LPD as a result of hyperprolactinemia appears to be a different entity from that due to inadequate follicular phase FSH.

Topics

Reproductive Endocrinology > Luteal Phase Deficiency > Hormonal Profiles Infertility > Luteal Phase Defect > Pathophysiology Menstrual Cycle > Follicular Phase > FSH Dynamics

luteal phase defect FSH levels follicular phase, luteal phase deficiency endometrial biopsy gonadotropins, low FSH follicular phase corpus luteum insufficiency, Cook Rao Yussman luteal phase defect hormones, luteal phase defect progesterone estrogen midluteal, FSH LH ratio early follicular phase LPD, inadequate follicular development luteal phase defect, luteal phase defect versus hyperprolactinemia etiology, corpus luteum quality follicular growth FSH, endometrial biopsy confirmed luteal insufficiency hormone profiles

PMID 6407879 6407879 DOI 10.1016/s0015-0282(16)47175-x 10.1016/s0015-0282(16)47175-x

Cite this article

Cook, C. L., Rao, C. V., & Yussman, M. A. (1983). Plasma gonadotropin and sex steroid hormone levels during early, midfollicular, and midluteal phases of women with luteal phase defects. *Fertility and sterility*, *40*(1), 45-48. https://doi.org/10.1016/s0015-0282(16)47175-x

Keywords

Adnexal Diseases/blood, Adult, Corpus Luteum/physiopathology, Estrogens/blood, Female, Follicle Stimulating Hormone/blood, Follicular Phase, Gonadotropins/blood, Humans, Luteinizing Hormone/blood, Menstruation, Menstruation Disturbances/blood, Progesterone/blood, Estrogens, Gonadotropins, Progesterone, Luteinizing Hormone, Follicle Stimulating Hormone

Plasma gonadotropin and sex steroid hormone levels during early, midfollicular, and midluteal phases of women with luteal phase defects

Abstract

Topics

Cite this article

Keywords

Related articles

The corpus luteum insufficiency: a multifactorial disease

Neonatal characteristics of children conceived with in vitro fertilization or intrauterine insemination compared with sibling births from unassisted conceptions

Disordered eating behaviors during adolescence and risk of endometriosis: a prospective cohort study

"Reply of the authors: ""Response to ""The illusion of reproductive choice: how restorative reproductive medicine violates informed consent for infertility treatment"""""