Neuropeptide levels in premenstrual syndrome

Chuong CJ, Kao PC, Bergstralh EJ, Go VL, Coulam CB

doi:10.1016/s0015-0282(16)49034-5

Neuropeptide levels in premenstrual syndrome

C B Coulam, Cheng‐Ming Chuong, Vay Liang W. Go, E J Bergstralh, P C Kao

Houston Methodist ROR
Mayo Clinic ROR

Fertility and Sterility, 44(6), 760-765

DOI 10.1016/s0015-0282(16)49034-5 PMID 2934273

Abstract

To determine whether changes in circulating levels of neuropeptides are associated with symptoms of premenstrual syndrome (PMS), 20 women with the diagnosis of PMS and 20 asymptomatic subjects were studied. The premenstrual beta-endorphin levels were significantly lower in PMS patients (P = 0.0001). The decrease in beta-endorphin levels during the luteal phase, compared with the follicular phase, in PMS patients was also significant (P = 0.0002). Neurotensin, human pancreatic peptide, vasoactive intestinal polypeptide, gastrin, and bombesin-like immunoreactivity levels did not reveal significant changes between days 7 and 25 in patients with PMS.

Topics

Menstrual Cycle > Premenstrual Syndrome > Neuroendocrine Factors Reproductive Endocrinology > Neuropeptides > Beta-Endorphin Menstrual Cycle > Premenstrual Syndrome > Pathophysiology

neuropeptide levels premenstrual syndrome beta-endorphin, PMS beta-endorphin decrease luteal phase deficiency, premenstrual syndrome circulating neuropeptides neurotensin, Chuong Coulam neuropeptide PMS endorphin levels, beta-endorphin follicular luteal phase premenstrual syndrome, premenstrual syndrome neuroendocrine etiology neuropeptides, opioid peptide deficiency premenstrual symptoms, vasoactive intestinal polypeptide gastrin PMS hormonal levels, low beta-endorphin luteal phase PMS pathophysiology, premenstrual syndrome biomarkers neuropeptide measurement

PMID 2934273 2934273 DOI 10.1016/s0015-0282(16)49034-5 10.1016/s0015-0282(16)49034-5

Cite this article

Chuong, C. J., Coulam, C. B., Kao, P. C., Bergstralh, E. J., & Go, V. L. (1985). Neuropeptide levels in premenstrual syndrome. *Fertility and sterility*, *44*(6), 760-765. https://doi.org/10.1016/s0015-0282(16)49034-5

Keywords

Adolescent, Adult, Bombesin/blood, Endorphins/blood, Female, Gastrins/blood, Humans, Menstrual Cycle, Middle Aged, Nerve Tissue Proteins/blood, Neurotensin/blood, Pancreatic Polypeptide/blood, Premenstrual Syndrome/blood, Vasoactive Intestinal Peptide/blood, beta-Endorphin, Endorphins, Gastrins, Nerve Tissue Proteins, Vasoactive Intestinal Peptide, Neurotensin, Pancreatic Polypeptide, beta-Endorphin, Bombesin

Neuropeptide levels in premenstrual syndrome

Abstract

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Cite this article

Keywords

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