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Neuropeptide levels in premenstrual syndrome

Chuong CJ et al., 1985

Fertility and sterility, 44(6), 760-765

DOI 10.1016/s0015-0282(16)49034-5 PMID 2934273 Source

Abstract

To determine whether changes in circulating levels of neuropeptides are associated with symptoms of premenstrual syndrome (PMS), 20 women with the diagnosis of PMS and 20 asymptomatic subjects were studied. The premenstrual beta-endorphin levels were significantly lower in PMS patients (P = 0.0001). The decrease in beta-endorphin levels during the luteal phase, compared with the follicular phase, in PMS patients was also significant (P = 0.0002). Neurotensin, human pancreatic peptide, vasoactive intestinal polypeptide, gastrin, and bombesin-like immunoreactivity levels did not reveal significant changes between days 7 and 25 in patients with PMS.

Topics

Menstrual Cycle > Disorders > PMDDReproductive Endocrinology > Luteal Phase > PhysiologyMenstrual Cycle > Biomarkers > Hormonal
beta endorphin premenstrual syndrome, neuropeptide levels luteal phase, pms hormonal changes, premenstrual symptoms beta endorphin, luteal phase neurochemistry, pms neuropeptide research, premenstrual mood changes biochemistry, beta endorphin menstrual cycle variation, neurotensin premenstrual syndrome, vasoactive intestinal peptide pms, luteal phase dysfunction neuropeptides

Cite this article

Chuong, C. J., Kao, P. C., Bergstralh, E. J., Go, V. L., & Coulam, C. B. (1985). Neuropeptide levels in premenstrual syndrome. *Fertility and sterility*, *44*(6), 760-765. https://doi.org/10.1016/s0015-0282(16)49034-5

Keywords

Adolescent, Adult, Bombesin, Endorphins, Female, Gastrins, Humans, Menstrual Cycle, Middle Aged, Nerve Tissue Proteins, Neurotensin, Pancreatic Polypeptide, Premenstrual Syndrome, Vasoactive Intestinal Peptide, beta-Endorphin

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