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Natural progesterone and antihypertensive action

Rylance PB et al., 1985

British medical journal (Clinical research ed.), 290(6461), 13-14

DOI 10.1136/bmj.290.6461.13 PMID 3917316 Source

Abstract

In a placebo controlled, double blind crossover study natural progesterone was given by mouth, in increasing doses, to six men and four postmenopausal women with mild to moderate hypertension who were not receiving any other antihypertensive drugs. When compared with values recorded before treatment and during administration of placebo progesterone caused a significant reduction in blood pressure, suggesting that progesterone has an antihypertensive action rather than a hypertensive one as has been previously thought. This possible protective effect of progesterone should be investigated further.

Topics

Reproductive Endocrinology > Progesterone > SupplementationReproductive Endocrinology > Progesterone > PhysiologyRRM Methods > NaProTECHNOLOGY > Protocol
natural progesterone blood pressure, bioidentical progesterone hypertension, progesterone antihypertensive effects, natural progesterone cardiovascular benefits, oral micronized progesterone blood pressure reduction, progesterone supplementation hypertension treatment, bioidentical hormone blood pressure, progesterone protective cardiovascular effects, natural progesterone vs synthetic progestins, luteal phase support hypertension, micronized progesterone clinical benefits

Cite this article

Rylance, P. B., Brincat, M., Lafferty, K., De Trafford, J. C., Brincat, S., Parsons, V., & Studd, J. W. (1985). Natural progesterone and antihypertensive action. *British medical journal (Clinical research ed.)*, *290*(6461), 13-14. https://doi.org/10.1136/bmj.290.6461.13

Keywords

Adult, Aged, Clinical Trials As Topic, Double-Blind Method, Female, Humans, Hypertension, Male, Menopause, Middle Aged, Posture, Progesterone

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