Measurement of serum LH, FSH, estradiol and progesterone in disorders of the human menstrual cycle: the inadequate luteal phase

  • University of Iowa Hospitals and Clinics ROR

The Journal of Clinical Endocrinology and Metabolism, 39(1), 145-149

DOI 10.1210/jcem-39-1-145 PMID 4835128

Abstract

The irregular menses experienced by obese and/or hirsute women were studied by daily measurement of serum LH, FSH, estradiol (E2) and progesterone (P). During 8 cycles of 24 to 157 days, each episode of menstrual bleeding was preceded by hormonal evidence of follicular maturation and corpus luteum formation. The premenstrual fluctuations of LH and E2 were not different from those observed in normal cycles. Although the luteal phase was of more than 10 days' duration, progesterone secretion was subnormal during each cycle. Serum FSH was low throughout the time preceding the LH/FSH surge. These data suggest that inadequate corpus luteum progesterone secretion may be characteristic of the menstrual cycles in oligomenorrheic, obese infertile women.

Topics

inadequate luteal phase serum progesterone LH FSH estradiol, Sherman Korenman luteal phase defect hormone measurement, obese hirsute women oligomenorrhea luteal insufficiency, daily hormone measurement irregular menstrual cycles, subnormal progesterone secretion corpus luteum oligomenorrhea, low FSH follicular phase inadequate luteal function, obesity hirsutism anovulation progesterone deficiency infertility, menstrual cycle disorders hormone profiles LH FSH estradiol progesterone, follicular maturation corpus luteum formation irregular cycles, luteal phase deficiency pathophysiology hormonal characterization
PMID 4835128 4835128 DOI 10.1210/jcem-39-1-145 10.1210/jcem-39-1-145

Cite this article

Sherman, B. M., & Korenman, S. G. (1974). Measurement of serum LH, FSH, estradiol and progesterone in disorders of the human menstrual cycle: the inadequate luteal phase. *The Journal of clinical endocrinology and metabolism*, *39*(1), 145-149. https://doi.org/10.1210/jcem-39-1-145

Related articles