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Low-dosage clomiphene therapy in the treatment of infertility due to defective ovulation

Barrett CT et al., 1974

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 48(34), 1456-1458

PMID 4853045 Source

Abstract

SUMMARY The use of clomiphene in gradually increasing doses, in cases of infertility due to anovulation, oligo-ovulation and inadequate luteal phase, led to a high pregnancy rate, particularly in the initial stages of treatment. Although clomiphene is a relatively safe and inexpensive drug, there is a possibility that high doses in repeated cycles may adversely affect fertility by its anti-oestrogenic effect. It is therefore suggested that therapy be commenced with a lower dosage than that generally recommended.

Topics

Infertility > Female Factor > Ovulatory DysfunctionReproductive Endocrinology > Ovulation > InductionReproductive Endocrinology > Luteal Phase > Deficiency
low dose clomiphene ovulation induction, clomiphene citrate anovulation treatment, clomid luteal phase deficiency, low dose clomid infertility, ovulation induction minimal stimulation, clomiphene oligo-ovulation, inadequate luteal phase clomiphene treatment, clomiphene dosage ovulatory dysfunction, anti-estrogenic effects clomiphene, clomid fertility outcomes

Cite this article

Barrett, C. T., & Hakim, C. A. (1974). Low-dosage clomiphene therapy in the treatment of infertility due to defective ovulation. *South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde*, *48*(34), 1456-1458.

Keywords

Abortion, Spontaneous, Adult, Amenorrhea, Body Temperature, Clomiphene, Female, Humans, Infertility, Ovulation, Pregnancy, Ectopic, Multiple, Twins

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