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Indispensability of the human corpus luteum in the maintenance of early pregnancy. Luteectomy evidence

Csapo AI et al., 1978

Obstetrical & gynecological survey, 33(2), 69-81

DOI 10.1097/00006254-197802000-00001 PMID 341008 Source

Abstract

Following Fraenkel's discovery, demonstrating that the rabbit corpora lutea are indispensable in pregnancy maintenance, Corner and Allen showed (1) in a series of now classic studies that luteectomy predictably terminates pregnancy, except when progesterone is provided as substitution therapy. Despite the clarity of these demonstrations and the accumulation of complementary data over 40 years (2, 3, 4), many investigators held the view that the studies in the rabbit model failed to establish a basic biological law of broad …

Topics

Reproductive Endocrinology > Progesterone > PhysiologyReproductive Endocrinology > Luteal Phase > PhysiologyPregnancy > Outcomes > Miscarriage Rates
corpus luteum early pregnancy maintenance, luteectomy pregnancy termination, progesterone indispensable pregnancy, luteal phase progesterone support, corpus luteum physiology pregnancy, progesterone substitution therapy pregnancy, early pregnancy progesterone requirements, luteal function first trimester, corner allen progesterone studies, corpus luteum ablation pregnancy loss

Cite this article

Csapo, A. I., & Pulkkinen, M. (1978). Indispensability of the human corpus luteum in the maintenance of early pregnancy. Luteectomy evidence. *Obstetrical & gynecological survey*, *33*(2), 69-81. https://doi.org/10.1097/00006254-197802000-00001

Keywords

Abortion, Induced, Adult, Corpus Luteum, Estradiol, Female, Humans, Menstruation, Oxytocin, Pregnancy, Pregnancy Maintenance, Pregnancy Trimester, First, Pressure, Progesterone, Prostaglandins F, Uterus

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