In-vitro sperm selection for intracytoplasmic sperm injection (Physiological ICSI or PICSI) is crucial as it has a direct influence on the paternal contribution of preimplantation embryogenesis. Men with oligozoospermia who require ICSI often demonstrate compromised DNA integrity and increased chromosomal aberrations of the sperms in their semen. Studies have shown that embryos resulting from ICSI in those men have higher risk of sex chromosome disomies, chromosomal aneuploidies, de novo numerical chromosomal aberrations and cytogenetically detectable structural chromosomal aberrations. Although the primary candidates for ICSI are oligozoospermic men, there is an increase in the use of ICSI; therefore, more couples are potentially exposed to those potential risks.
MA, B. (2022). Evaluation of Sperm Selection Technique Using Hyaluronic Acid Binding During Icsi; a Randomized Controlled Trial. *Obstetrics Gynecology and Reproductive Sciences*, *6*(4), 01-07. https://doi.org/10.31579/2578-8965/121
MA B. Evaluation of Sperm Selection Technique Using Hyaluronic Acid Binding During Icsi; a Randomized Controlled Trial. JOGRS. 2022;6(4):01-07. doi:10.31579/2578-8965/121
MA, Behery. "Evaluation of Sperm Selection Technique Using Hyaluronic Acid Binding During Icsi; a Randomized Controlled Trial." *Obstetrics Gynecology and Reproductive Sciences*, vol. 6, no. 4, 2022, pp. 01-07.
Male infertility is an increasing and serious medical concern, though the mechanism remains poorly understood. Impaired male reproductive function affects approximately half of infertile couples world...
Nedelcu S et al., 2024
Open Access
Human reproduction open
Study Question: Can semen parameters predict long-term health outcomes in men? Summary Answer: There is a lack of evidence to suggest a higher risk of comorbidities in men with poor semen concentratio...
The role of sperm DNA fragmentation index (DFI) in investigating fertility, embryonic development, and pregnancy is of academic interest. However, there is ongoing controversy regarding the impact of ...
Andrology > Sperm DNA > FragmentationAndrology > Sperm DNA > Clinical SignificancePregnancy > Recurrent Loss > Etiology
Jankowska K et al., 2022
Open Access
Life (Basel, Switzerland)
Biochemical markers of spermatogenesis and fertility assessment are important in the practical management of infertile males and the determination of an individual’s prognosis. We performed an analysi...