To examine potential risk factors associated with the success rate following fallopian tube recanalization (FTR) in infertile women with obstruction of the proximal fallopian tube.
Methods
We retrospectively studied patients who underwent FTR for tubal obstructive infertility between January 2016 and December 2018 at the Third Affiliated Hospital of Guangzhou Medical University. FTR was performed using a catheter and guidewire system to clear tubal obstruction. Predictive factors potentially associated with the success rate were assessed by logistic regression.
Results
A total of 762 patients were included. Multivariable analysis showed that age (odds ratio [OR] = 2.38, 95% confidence interval [CI]: 1.24-4.58), infertility type (OR = 2.82, 95% CI: 1.36-6.21), history of ectopic pregnancy (OR = 7.87, 95% CI: 4.05-15.81), history of abdominal surgery (OR = 4.30, 95% CI: 2.22-8.60), history of artificial abortion curettage (OR = 4.08, 95% CI: 2.12-8.03), and duration of infertility (OR = 2.03, 95% CI: 1.06-3.85) were independently associated with postoperative tubal patency.
Conclusions
Our findings suggest that risk factors, such as age ≥35 years, secondary infertility, duration of infertility ≥5 years, and histories of ectopic pregnancy, abdominal surgery, and artificial abortion curettage, affect the success rate of FTR. These factors may also predict surgical success in treating tubal obstructive infertility.
PMID 33322979 33322979 DOI 10.1177/0300060520979218 10.1177/0300060520979218
Cite this article
Shen, H., Cai M, M., Chen, T., Zheng, D., Huang, J., Zhou, M., He, W., Li, Y., & Tan, Q. (2020). Factors affecting the success of fallopian tube recanalization in treatment of tubal obstructive infertility. The Journal of international medical research, 48(12), 300060520979218. https://doi.org/10.1177/0300060520979218
Shen H, Cai M M, Chen T, Zheng D, Huang J, Zhou M, et al. Factors affecting the success of fallopian tube recanalization in treatment of tubal obstructive infertility. J Int Med Res. 2020;48(12):300060520979218. doi:10.1177/0300060520979218
Shen, Huawei, et al. "Factors affecting the success of fallopian tube recanalization in treatment of tubal obstructive infertility." The Journal of international medical research, vol. 48, no. 12, 2020, pp. 300060520979218.
Infertility is a world-wide problem, defined as failure to achieve pregnancy after 12 months of regular unprotected sexual intercourse. There are multiple causes for infertility involving both male and female factors. Fallopian tube occlusion is a common reason for female infertility. The initial attempts to treat proximal obstruction involved the use of a whalebone bougie positioned in the uterine cornua to dilate the proximal tube by Smith as early as 1849. Fluoroscopic fallopian tube recanalization for the treatment of infertility was first described in 1985. Since that time, there have been over 100 papers describing various methods for recanalization of occluded fallopian tubes. Fallopian tube recanalization is a minimally invasive procedure which is performed on an outpatient basis. It should be a first line therapy for patients with proximal occlusion of fallopian tubes.
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