Journal of Human Reproductive Sciences, 5(2), 166-169
Use of metformin throughout pregnancy in women with polycystic ovary syndrome (PCOS) has shown to reduce the rates of early pregnancy loss, preterm labor, and prevention of fetal growth restriction. Metformin has been shown to have encouraging effects on several metabolic aspects of polycystic ovarian syndrome, such as insulin sensitivity, plasma glucose concentration and lipid profile and since women with PCOS are more likely than healthy women to suffer from pregnancy-related problems like early pregnancy loss, gestational diabetes mellitus and hypertensive states in pregnancy, the use of metformin therapy in these patients throughout pregnancy may have beneficial effects on early pregnancy loss and development of gestational diabetes.
Kumar, P., & Khan, K. (2012). Effects of metformin use in pregnant patients with polycystic ovary syndrome. *Journal of human reproductive sciences*, *5*(2), 166-169. https://doi.org/10.4103/0974-1208.101012
Kumar P, Khan K. Effects of metformin use in pregnant patients with polycystic ovary syndrome. J Hum Reprod Sci. 2012;5(2):166-169. doi:10.4103/0974-1208.101012
Kumar, Pratap, and Kashif Khan. "Effects of metformin use in pregnant patients with polycystic ovary syndrome." *Journal of human reproductive sciences*, vol. 5, no. 2, 2012, pp. 166-169.
Metformin, PCOS, Pregnancy