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Cyclicity of breast tenderness and night-time vasomotor symptoms in mid-life women: information collected using the Daily Perimenopause Diary

Hale GE et al., 2003

Climacteric : the journal of the International Menopause Society, 6(2), 128-139

PMID 12841883 Source

Abstract

Objective

The purpose was to explore cyclicity of breast tenderness and vasomotor symptoms in menstruating mid-life women using the Daily Perimenopause Diary.

Methods

Untreated mid-life women from a convenience sample completed the Daily Perimenopause Diary for clinical (n = 14) or research (n = 10) assessments. Breast tenderness, sleep disturbance and day and night vasomotor intensity were rated on a 0-4 scale with vasomotor number as a count. Daily oral temperature data were analyzed using the Quantitative Basal Temperature algorithm to assess ovulation and estimate luteal phase length. Analysis of variance tested cyclicity using the mean of three 3-day windows (during flow, at mid-cycle and premenstrually).

Results

Ninety-eight complete flow-to-flow diaries (from 24 women, mean age 47 years, cycle length 27 +/- 6.4 (standard deviation) days) were available, with quantitative temperature data for 60 cycles in 16 women. Of assessed cycles, 90% were ovulatory; 25% had luteal phases < 10 days. Breast tenderness was maximal in the premenstrual window overall (p < 0.0001) and in the ovulatory subset. Night sweats were maximal premenstrually (p = 0.0035) except in anovulatory cycles. Daytime flushes were not cyclic (p = 0.1333) except in ovulatory cycles (p = 0.031).

Conclusion

Daily Perimenopause Diaries from mid-life women show premenstrual increases in breast tenderness and night sweats.

Topics

Diagnostics > Cycle Charting > Clinical UtilityMenstrual Cycle > Biomarkers > TemperaturePerimenopause/Menopause > Symptoms > VasomotorReproductive Endocrinology > Luteal Phase > Deficiency
perimenopause daily symptom tracking, breast tenderness menstrual cycle, night sweats premenstrual, basal body temperature perimenopause, ovulation tracking mid-life women, luteal phase deficiency perimenopause, daily perimenopause diary, vasomotor symptoms menstrual cycle, hot flashes cyclic pattern, cycle charting perimenopause, premenstrual symptoms quantitative tracking, short luteal phase mid-life

Cite this article

Hale, G. E., Hitchcock, C. L., Williams, L. A., Vigna, Y. M., & Prior, J. C. (2003). Cyclicity of breast tenderness and night-time vasomotor symptoms in mid-life women: information collected using the Daily Perimenopause Diary. *Climacteric : the journal of the International Menopause Society*, *6*(2), 128-139.

Keywords

Adult, Body Temperature, Breast Diseases, British Columbia, Circadian Rhythm, Climacteric, Female, Hot Flashes, Humans, Menstrual Cycle, Middle Aged, New South Wales, Sleep Wake Disorders, Surveys and Questionnaires, Western Australia

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