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Clinical discussion of the relationship between endometriosis and epithelial ovarian cancer

Zhang Y et al., 2001

Zhang Y, Huang H, Lian L

Zhonghua Fu Chan Ke Za Zhi, 34(9), 544-546, 1999

Source PubMed

Abstract

Objective

To analyse the relationship between endometriosis and epithelial ovarian cancer.

Methods

We analyzed retrospectively the 20 cases associated with endometriosis in 371 cases of epithelial ovarian cancer, and these 20 cases were also compared with the left 351 cases not associated with endometriosis(including endomtriod carcinoma 38 cases and clear cell carcinoma 39 cases).

Results

Among 20 cases, endomtriod carcinoma and clear cell carcinoma were most frequently associated with endometriosis, with 11 cases and 7 cases respectively, there was also 1 case of gland carcinoma and 1 case of serous papillary carcinoma. Cases of carcinomas associated with endometriosis had higher pathological grade and 5-year survival probability (Kaplan-Meier method) than those cases not associated with endometriosis.

Conclusions

There is a close relationship between endometriosis and ovarian endomtriod carcinoma and clear cell carcinoma, the malignant transformation of endometriosis foci may be an important origin of them. Drug therapy is recommended for endomtriosis after the operation. In the treatment of endomtriod carcinoma and clear cell carcinoma, progestin can be used as an accessory method.

Topics

Endometriosis > Pathophysiology > MechanismsGeneral OB/GYN > Epidemiology > Prevalence
endometriosis ovarian cancer risk, malignant transformation endometriosis, endometrioid carcinoma endometriosis, clear cell carcinoma endometriosis, endometriosis cancer surveillance, progestin therapy ovarian cancer, endometriosis foci malignancy, epithelial ovarian cancer endometriosis, endometriosis long term outcomes, ovarian cancer endometriosis association, endometriosis surgical treatment outcomes, progesterone endometrial cancer prevention

Cite this article

Zhang, Y., Huang, H., & Lian, L. (2001). [Clinical discussion of the relationship between endometriosis and epithelial ovarian cancer]. *Zhonghua Fu Chan Ke Za Zhi*, *34*(9), 544-546.

Keywords

Adenocarcinoma, Clear Cell, Adult, Aged, Carcinoma, Endometrioid, Cystadenocarcinoma, Papillary, Endometriosis, Female, Humans, Middle Aged, Ovarian Neoplasms

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