The Medical and Surgical Practice of NaProTECHNOLOGY, 281-284, 2004

Chapter 23: Differences Between Laboratories

Thomas W Hilgers

Author affiliations
  • Pope Paul VI Institute for the Study of Human Reproduction, Omaha, Nebraska. ROR
Read at source

Abstract

Serum estradiol and progesterone assays vary substantially across laboratories because of differences in antibody specificity, calibration standards, detection platforms, and quality-control practices, meaning that a value within one laboratory's generic reference range may represent a clinically significant deficiency when interpreted against NaPro Peak-day-specific norms. NaProTECHNOLOGY requires consistent use of a single reference laboratory and interpretation relative to cycle-phase-specific NaPro standards rather than broad lab-generated reference intervals, to avoid missing subtle follicular or luteal phase defects that standard reporting would classify as normal.

Topics

why do progesterone results differ between labs, can I compare my hormone results to NaProTechnology charts, are hormone reference ranges the same at every laboratory, what is coefficient of variation in a hormone assay, biologic vs assay variation in reproductive hormone testing, how many specimens needed to correlate labs for progesterone, why does my progesterone level vary by laboratory, inter-laboratory variability progesterone pregnancy

Cite this article

Hilgers, T. W. (2004). Chapter 23: Differences Between Laboratories. *The Medical and Surgical Practice of NaProTECHNOLOGY*, 281-284.

Related articles