To evaluate the effect of supernumerary preovulatory follicular reduction as an approach to avoid multiple pregnancies in ovulation induction or superovulation cycles.
Design
Retrospective study.
Setting
Tertiary referral center.
PATIENT(S): In 26 cycles, 24 patients underwent ovulation induction or superovulation with either clomiphene citrate or hMG.
INTERVENTION(S): Selective follicle aspiration was performed before hCG administration.
MAIN OUTCOME MEASURE(S): Clinical pregnancy rate and numbers of multiple pregnancies.
RESULT(S): A mean number of 4.5 follicles with a diameter > or =15 mm and a mean number of 4.5 follicles with a diameter < or =14 mm were observed before hCG administration. A mean number of 2.3 follicles with a diameter > or =15 mm and a mean number of 1.8 follicles with a diameter < or =14 mm were aspirated before the hCG administration. Seven singleton pregnancies (26.9% per cycle) ensued from the treatment.
CONCLUSION(S): Aspiration of supernumerary follicles after ovulation induction or superovulation seems to be a valid approach to avoid multiple pregnancies without affecting pregnancy rate.
PMID 11591420 11591420 DOI 10.1016/s0015-0282(01)02379-2 10.1016/s0015-0282(01)02379-2
Cite this article
Albano, C., Platteau, P., Nogueira, D., Cortvrindt, R., Smitz, J., & Devroey, P. (2001). Avoidance of multiple pregnancies after ovulation induction by supernumerary preovulatory follicular reduction. *Fertility and sterility*, *76*(4), 820-822. https://doi.org/10.1016/s0015-0282(01)02379-2
Albano C, Platteau P, Nogueira D, Cortvrindt R, Smitz J, Devroey P. Avoidance of multiple pregnancies after ovulation induction by supernumerary preovulatory follicular reduction. Fertil Steril. 2001;76(4):820-822. doi:10.1016/s0015-0282(01)02379-2
Albano, C., et al. "Avoidance of multiple pregnancies after ovulation induction by supernumerary preovulatory follicular reduction." *Fertility and sterility*, vol. 76, no. 4, 2001, pp. 820-822.
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