Fertility and sterility, 76(4), 820-822
To evaluate the effect of supernumerary preovulatory follicular reduction as an approach to avoid multiple pregnancies in ovulation induction or superovulation cycles.
Retrospective study.
Tertiary referral center. PATIENT(S): In 26 cycles, 24 patients underwent ovulation induction or superovulation with either clomiphene citrate or hMG. INTERVENTION(S): Selective follicle aspiration was performed before hCG administration. MAIN OUTCOME MEASURE(S): Clinical pregnancy rate and numbers of multiple pregnancies. RESULT(S): A mean number of 4.5 follicles with a diameter > or =15 mm and a mean number of 4.5 follicles with a diameter < or =14 mm were observed before hCG administration. A mean number of 2.3 follicles with a diameter > or =15 mm and a mean number of 1.8 follicles with a diameter < or =14 mm were aspirated before the hCG administration. Seven singleton pregnancies (26.9% per cycle) ensued from the treatment. CONCLUSION(S): Aspiration of supernumerary follicles after ovulation induction or superovulation seems to be a valid approach to avoid multiple pregnancies without affecting pregnancy rate.
Albano, C., Platteau, P., Nogueira, D., Cortvrindt, R., Smitz, J., & Devroey, P. (2001). Avoidance of multiple pregnancies after ovulation induction by supernumerary preovulatory follicular reduction. *Fertility and sterility*, *76*(4), 820-822. https://doi.org/10.1016/s0015-0282(01)02379-2
Albano C, Platteau P, Nogueira D, Cortvrindt R, Smitz J, Devroey P. Avoidance of multiple pregnancies after ovulation induction by supernumerary preovulatory follicular reduction. Fertil Steril. 2001;76(4):820-822. doi:10.1016/s0015-0282(01)02379-2
Albano, C., et al. "Avoidance of multiple pregnancies after ovulation induction by supernumerary preovulatory follicular reduction." *Fertility and sterility*, vol. 76, no. 4, 2001, pp. 820-822.
Adult, Female, Follicular Phase, Humans, Ovarian Follicle, Ovulation Induction, Pregnancy, Pregnancy Rate, Multiple, Retrospective Studies, Suction