25-Hydroxyvitamin D in the range of 20 to 100 ng/mL and incidence of kidney stones

American journal of public health, 104(9), 1783-1787

DOI 10.2105/AJPH.2013.301368 PMID 24134366 Source

Abstract

Objectives

Increasing 25-hydroxyvitamin D serum levels can prevent a wide range of diseases. There is a concern about increasing kidney stone risk with vitamin D supplementation. We used GrassrootsHealth data to examine the relationship between vitamin D status and kidney stone incidence.

Methods

The study included 2012 participants followed prospectively for a median of 19 months. Thirteen individuals self-reported kidney stones during the study period. Multivariate logistic regression was applied to assess the association between vitamin D status and kidney stones.

Results

We found no statistically significant association between serum 25-hydroxyvitamin D and kidney stones (P = .42). Body mass index was significantly associated with kidney stone risk (odds ratio = 3.5; 95% confidence interval = 1.1, 11.3).

Conclusions

We concluded that a serum 25-hydroxyvitamin D level of 20 to 100 nanograms per milliliter has no significant association with kidney stone incidence.

Topics

vitamin d kidney stones, 25 hydroxyvitamin d safety, vitamin d supplementation side effects, optimal vitamin d levels, vitamin d3 stone formation, calcium kidney stone risk, vitamin d toxicity concerns, body mass index kidney stones, vitamin d serum levels safety

Cite this article

Nguyen, S., Baggerly, L., French, C., Heaney, R. P., Gorham, E. D., & Garland, C. F. (2013). 25-Hydroxyvitamin D in the range of 20 to 100 ng/mL and incidence of kidney stones. *American journal of public health*, *104*(9), 1783-1787. https://doi.org/10.2105/AJPH.2013.301368

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