The International Agency for Research on Cancer (IARC) Monographs on the carcinogenic risk to humans concluded that combined oral oestrogen–progestogen contraceptives are carcinogenic to humans (IARC, 2007). This evaluation was made on the basis of increased risks for cancer of the breast (among current and recent users only), cervix and liver (in populations that are at low risk for hepatitis B viral infection). There is also convincing evidence in humans that these agents confer a protective effect against cancer of the endometrium and ovary.
cancer attributable hormone exposure, HRT cancer risk population, oral contraceptive cancer attributable fraction, hormone replacement therapy cancer burden, estrogen cancer risk UK, hormonal therapy cancer incidence, cancer prevention hormone avoidance, breast cancer hormonal risk, endometrial cancer HRT, ovarian cancer hormone use
PMID 22158320 22158320 DOI 10.1038/bjc.2011.483 10.1038/bjc.2011.483
Cite this article
Parkin, D. M. (2011). 10. Cancers attributable to exposure to hormones in the UK in 2010. *British journal of cancer*, *105 Suppl 2*(Suppl 2), S42-S48. https://doi.org/10.1038/bjc.2011.483
Parkin DM. 10. Cancers attributable to exposure to hormones in the UK in 2010. Br J Cancer. 2011;105 Suppl 2(Suppl 2):S42-S48. doi:10.1038/bjc.2011.483
Parkin, Donald Maxwell. "10. Cancers attributable to exposure to hormones in the UK in 2010." *British journal of cancer*, vol. 105 Suppl 2, no. Suppl 2, 2011, pp. S42-S48.
Segarra I et al., 2023
Open Access
Frontiers in Medicine
Hormone-based contraception disrupts hormonal balance, creating artificial states of anovulation and threatening women's health. We reviewed its main adverse effects and mechanisms on accelerated ovar...
Johansson T et al., 2023
Open Access
Epidemiology and Psychiatric Sciences
Aim: Research on the effect of oral contraceptive (OC) use on the risk of depression shows inconsistent findings, especially in adult OC users. One possible reason for this inconsistency is the omissi...
Zareian B et al., 2022
Open Access
BMC Women's Health
Background: The incidence of depression in human females rises steadily throughout adolescence, a critical period of pubertal maturation marked by increasing levels of gonadal hormones including estro...
Khafagy GM et al., 2021
Open Access
Korean Journal of Family Medicine
Background: Contraceptive agents are widely used by women of reproductive age, and resulting depression is the most common side effect of this usage. This study aimed to study the effect of monthly in...